A filling needle can be used in a tube set for transferring a flowable medium, in particular a pharmaceutical product. The filling needle has a needle end for temporary insertion in a filling vessel. Furthermore, the filling needle has a connector end for connecting the filling needle to a filling vessel, via which the medium can be supplied to the filling needle. An inner tube lumen of the filling needle is defined by an inner tube layer made of silicone. The result is a filling needle that can be manufactured inexpensively.

A filling needle can be used in a tube set for transferring a flowable medium, in particular a pharmaceutical product. The filling needle has a needle end for temporary insertion in a filling vessel. Furthermore, the filling needle has a connector end for connecting the filling needle to a filling vessel, via which the medium can be supplied to the filling needle. An inner tube lumen of the filling needle is defined by an inner tube layer made of silicone. The result is a filling needle that can be manufactured inexpensively.

The aspects of the disclosed embodiments relates to methods for optimization of the sliding properties of urinary catheters. The urinary catheters are first treated with a non-equilibrium gaseous plasma sustained in reactive gases or a mixture of a reactive gas with a noble gas. The first treatment enables a hydrophilic surface finish when oxygen is a reactive gas and an almost super-hydrophilic finish when the catheter is treated with hydrogen plasma followed by oxygen plasma. The hydrophilicity of the surface finish obtained upon the first plasma treatment is beneficial for adhering a layer of water solution of chitosan, which spreads uniformly on the entire outer surface of the catheter. The catheter with a layer of water solution of chitosan is dried and then treated with plasma containing an oxidative gas for better absorption of water by the dried chitosan film.

The present invention provides a thermoplastic elastomer (TPE), in particular a polyurethane-based thermoplastic elastomer (TPU), that has exceptional elongation, strength, and wear resistance, and in particular has exceptional wear resistance. The present invention provides: a thermoplastic elastomer composition containing A) a thermoplastic urethane elastomer composition having A1) at least one polyol selected from the group consisting of polyether polyols, polyesterpolyols, and polycarbonate polyols, A2) a diisocyanate, and A3) a chain extender, and B) polyrotaxane formed by arranging blocking groups, at both ends of pseudo-polyrotaxane formed by inclusion of the openings of cyclic molecules in a shape skewered by linear molecules, so that the cyclic molecules are not eliminated; and a thermoplastic elastomer derived from this composition.

A cable includes a silicone rubber coating including microparticles and cavities as an outermost coating. A medial hollow tube includes a silicone rubber coating including microparticles and cavities as an outermost coating or an innermost coating. The microparticles may be at least one kind of microparticle selected from silicone resin microparticle, silicone rubber microparticle and silica microparticle. The microparticles may have hardness higher than a hardness of silicone rubber constituting the silicone rubber coating.

A cable includes a silicone rubber coating including microparticles and cavities as an outermost coating. A medial hollow tube includes a silicone rubber coating including microparticles and cavities as an outermost coating or an innermost coating. The microparticles may be at least one kind of microparticle selected from silicone resin microparticle, silicone rubber microparticle and silica microparticle. The microparticles may have hardness higher than a hardness of silicone rubber constituting the silicone rubber coating.

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising: (A) at least one taurinamide derivative, (B) at least one compound selected from the group consisting of biologically acceptable acids and biologically acceptable salts thereof; and (C) heparin at a low concentration.

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising: (A) at least one taurinamide derivative, (B) at least one compound selected from the group consisting of biologically acceptable acids and biologically acceptable salts thereof; and (C) heparin at a low concentration.

Deflectable catheters, hemostasis valves, and materials for the same are disclosed. The deflectable catheters and hemostasis valves can be made at least partially, if not entirely, from a fluoroelastomer and ePTFE combination. A deflectable region of the catheters can be articulated to form simple and/or complex curves.

A medical device includes a base layer, and a lubrication layer supported on at least a part of the base layer, wherein the lubrication layer contains a block copolymer (A) composed of a first constituting unit derived from a reactive monomer that has an epoxy group and a second constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, and a polymer (B) composed of a constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, wherein the block copolymer (A) is contained in a proportion of 20 to 80% by weight relative to the total weight of the block copolymer (A) and the polymer (B), and wherein the block copolymer (A) is crosslinked or polymerized to form a mesh structure.