The present invention provides methods for treating tumors in subjects by using a recombinant interferon (rSIFN-co), and optionally, methods for treating solid tumors, such as lung cancer, among others, with or without prior surgery, and as a first line or second line monotherapy or in combination with one or more other anti-tumor therapies. The present invention further provides non-surgical methods for eliminating tumors or reducing tumor sizes in subjects, and/or preventing postoperative tumor recurrence and/or metastases in subjects by using the recombinant interferon (rSIFN-co) which comprises a unique spatial configuration, alone or in conjunction with radiotherapy, chemotherapy, and/or one or more anti-tumor drugs such as biological agents, targeted drugs, small molecules, Traditional Chinese Medicine (TCM) and the like.

Multistage vaporizers, such as for use in medical treatment systems, as well as related methods are described. In one example, a multistage vaporizer includes a first reservoir configured to hold a liquid and one or more pumping transducers positioned in the first reservoir. The multistage vaporizer also includes a second reservoir and one or more vaporizing transducers positioned in the second reservoir. The one or more pumping transducers positioned in the first reservoir are configured to generate and move droplets of a liquid in the first reservoir to the second reservoir, and the one or more vaporizing transducers positioned in the second reservoir are configured to create a vapor of the liquid in the second reservoir.

A ball valve for use in a respiration circuit proving for selective gas flow between at least two outlets of the ball valve and a respiration circuit including the ball valve.

Disclosed are: a system comprising a gas circulation device capable of circulating hyperthermic gas in the peritoneal cavity and a temperature control device; and a system comprising a drug spray device for effectively spraying a drug in the peritoneal cavity together with gas. The systems of the present invention are used as systems for hyperthermic intraperitoneal chemotherapy and can maximize the anticancer therapy effect by more effectively delivering a small amount of an anticancer drug to cancer cells while maintaining the temperature of gas in the peritoneal cavity at a predetermined temperature.

A medicament delivery device includes a housing having a longitudinal axis, a container holder, an axially movable plunger adapted to be displaced along the longitudinal axis into the container holder, and an energy accumulating member arranged inside the housing and adapted for displacing the plunger along the longitudinal axis. The plunger includes an outer plunger rod and an inner plunger rod arranged at least partially inside the outer plunger rod, the inner plunger rod being threadedly engaged with the outer plunger rod and manually rotatable to displace the inner plunger rod along the longitudinal axis into the container holder.

The present invention relates to a control device for controlling an operation of an aerosol nebulizer system (30), said aerosol nebulizer system (30) comprising an aerosol generator (31) for nebulizing a liquid and a plurality of sensor units (38a, 38b, 38c, 38d, 38e), said control device (20) comprising: a communication unit (21), configured to establish a wireless communication connection and to perform data transmission with the aerosol nebulizer system (30), a sensor data control unit (22), configured to trigger a selection of sensor data related to the sensor units (38a, 38b, 38c, 38d, 38e) to be wirelessly transmitted to the control device (20).

A dispersion device includes a first dispersion generating system, a second dispersion generating system and an outlet end element including a first outlet corresponding to the first dispersion generating system and a second outlet corresponding to the second dispersion generating system.

A sublingual type medication delivery device includes a container body having a predetermined volume of solvent with a spray dispenser attached at one end of the container and at the opposite end of the container is a housing which contains medication to be discharged into the container and mixed with the solvent to form a diluted medication for fractional delivery of the medication over a period of time. The housing can either be a tablet crusher for introducing medicament in solid form into the container or the housing can be a capsule having liquid medicament that is delivered through a needle that pierces the capsule wall.

In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.

In one embodiment, the electronic vaping device includes a cartridge and a battery section. The cartridge and the battery section are connectable so as to define an air inlet between a portion of the cartridge and a portion of the battery section.