Vaporizer cartridges and vaporizer apparatuses, and methods for making, using, and/or delivering vapor to a user are described. In some aspects, leak-resistant vaporizer cartridges and/or apparatuses adapted for use with oil-based vaporizable materials including cannabis oils are described.

Vaporizer cartridges and vaporizer apparatuses, and methods for making, using, and/or delivering vapor to a user are described. In some aspects, leak-resistant vaporizer cartridges and/or apparatuses adapted for use with oil-based vaporizable materials including cannabis oils are described.

A hookah device (202) which attaches to a hookah (246). The hookah device (202) comprises a plurality of ultrasonic mist generator devices (201) for generating a mist for inhalation by a user. The hookah device (202) comprises a driver device (202) which controls the mist generator devices (201) to maximize the efficiency of mist generation by the mist generator devices (201) and optimize mist output from the hookah device (202).

This invention relates to a container (1) which is pre-filled or pre-fillable with one or more substances, such as a medical liquid and similar, comprising a squeezable activation compartment (2) intended to contain said one or more substances, a dispensing compartment (3) including a first portion (31) equipped with at least one dispensing member (311, 312, 314) of said one or more substances, and a second portion (32), wherein said second portion (32) of said dispensing compartment (3) and said activation compartment (2) are fluid-dynamically connected, and an activator element (4) arranged inside said container (1).

This invention also relates to a method for dispensing at least one substance by means of a container (1), and to a production method of a container (1).

Methods and compositions for treating mTBI, PTSD or mTBI with PTSD with psychedelic agents and N-acetylcysteine are provided. Nasal mist transducers for administration of one or more pharmaceutically active ingredients such as these as fine mist particles at preselected dosages and times are also provided.

A method is provided that includes intranasally dispensing nasal wash fluid into a nasal cavity of a subject such that the nasal wash fluid washes biological material into an oropharynx of the subject from (a) the nasal cavity, (b) a nasopharynx of the subject, or (c) the nasal cavity and the nasopharynx. The method further includes, thereafter, collecting a specimen sample that passed out of an anterior opening of an oral cavity of the subject and contains at least a portion of the biological material washed into the oropharynx by the nasal wash fluid. Thereafter, information is derived from extracellular vesicles present in the specimen sample. Other embodiments are also described.

A fluid dispensing device having an air expulsion system (200) with a pump (200) with an external body (210) containing a pump body (220; 270) with a pumping chamber (225) and a piston rod (230). The pump body has a proximal hollow body and a distal hollow body fixed to one another. The rod has a proximal rod part (231), a central rod part (232) and a distal rod part (233), the outside diameter of the central rod part (232) greater than the diameters of the other two. The central rod part supports a first seal (237) and a second seal (236), and the distal rod part supports a third seal (235). The proximal rod part has a central passage (234) extending beyond the first seal and opens laterally to the outside between the first and second seals. The distal hollow body contains a spring.

An atomiser, in particular an inhaler, for atomising a liquid active agent to form an aerosol, having, inter alia, an active agent reservoir, an atomiser nozzle and a pump arrangement, wherein a suction side of the pump arrangement leads into the active agent reservoir and a pressure side of the pump arrangement leads into the atomiser nozzle, and wherein the pump arrangement has a plunger that can be adjusted in a cylinder in the axial direction of the cylinder. A corresponding method is also described.

An atomiser, in particular an inhaler, for atomising a liquid active agent to form an aerosol, having, inter alia, an active agent reservoir, an atomiser nozzle and a pump arrangement, wherein a suction side of the pump arrangement leads into the active agent reservoir and a pressure side of the pump arrangement leads into the atomiser nozzle, and wherein the pump arrangement has a plunger that can be adjusted in a cylinder in the axial direction of the cylinder. A corresponding method is also described.

A positive air pressure delivery device includes a housing having an inhalation inlet, an inhalation outlet, and an interior cavity in fluid communication with the inhalation inlet and outlet. A pressurized fluid inlet includes an outlet orifice in fluid communication with the interior cavity between the inhalation inlet and outlet. A sound reducer baffle has a convex dome surface positioned downstream of and facing the outlet orifice in a spaced apart relationship therewith. One embodiment of the housings includes a body, an end cap and a baffle insert. In various embodiments, the positive air pressure delivery device may be used in combination with other therapy devices, including an OPEP and pressure indicator. A kit and method of using the device are also provided.