Vaporizer cartridges and vaporizer apparatuses, and methods for making, using and delivering vapor to a user, that are leak-resistant for use with cannabinoids. In particular, described herein are leak-resistant vaporizer cartridges and apparatuses adapted for use with oil-based vaporizable materials including cannabis oils.

An inhalation-synchronized fluid dispenser device having a body (10; 10′) provided with a mouthpiece (400), a fluid reservoir (100) containing a fluid and a propellant gas being mounted to slide axially in the body (10; 10′), a metering valve (200) including a valve member (210) assembled on the reservoir (100) for selectively dispensing the fluid. The device includes an actuator element (500, 500′, 500″; 550) movable and/or deformable between a non-actuation position and an actuation position; an inhalation-controlled trigger system including an inhalation-sensitive member (60, 61; 65, 66) deformable and/or movable under the effect of inhaling and when deformed and/or moved, moving and/or deforming the actuator element (500, 500′, 500″; 550) from its non-actuation position towards its actuation position; an electronic dose counter (1000); and a signal-transmitter (1100) for communicating, in particular communicating remotely, information relating to the actuations of the device.

An aerosol medicament delivery adapter comprises a first conduit, second conduit and a diverter element. The first conduit encloses a flow path chamber and extends between an upstream first end and a downstream second end. The second conduit comprises an aerosol medicament delivery conduit that includes an upstream first end adapted to be fluidly coupled to a particle generator, and a downstream second end luidly coupled to the first conduit at a Y-junction proximate the upstream first end of the first conduit. The diverter element comprises a flow diverter chamber disposed within the first conduit or the second conduit. The cylindrical flow diverter chamber includes a transitional flow cross-section and a principal axis, extending between a first end and a second end thereof. The diverter element creates flow eddies for enhancing an entrainment of aerosol particles, delivered via the second conduit, within a pressurized gas flow along the flow path within the first conduit.

An aerosol medicament delivery adapter comprises a first conduit, second conduit and a diverter element. The first conduit encloses a flow path chamber and extends between an upstream first end and a downstream second end. The second conduit comprises an aerosol medicament delivery conduit that includes an upstream first end adapted to be fluidly coupled to a particle generator, and a downstream second end luidly coupled to the first conduit at a Y-junction proximate the upstream first end of the first conduit. The diverter element comprises a flow diverter chamber disposed within the first conduit or the second conduit. The cylindrical flow diverter chamber includes a transitional flow cross-section and a principal axis, extending between a first end and a second end thereof. The diverter element creates flow eddies for enhancing an entrainment of aerosol particles, delivered via the second conduit, within a pressurized gas flow along the flow path within the first conduit.

An infectious aerosol capture mask (IACM) includes a face tent coupled to a suction tube adapter. The face tent includes a proximal opening configured to be disposed over the mouth and nose of a patient. The face tent further includes a distal opening with a smaller diameter than the proximal opening. A coupler is configured to secure the suction tube adapter to the distal opening of the face tent. The suction tube adapter includes a suction port configured to be coupled to a suction tube for active capture of infectious aerosol and left unconnected for passive capture of infectious aerosol. A viral filter is disposed between the suction port and the face tent to capture infectious aerosols expelled by the patient. The IACM further includes one or more one-way valves that are configured to permit airflow into the face tent.

The present invention provides pharmaceutical compositions comprising an antiseptic and a steroid, useful for treating a clinical symptom in a patient's airway (e.g., nose, lung, and sinus), wherein a gel containing the antiseptic is formed in situ upon instillation of the compositions onto a body cavity of a subject, as well as methods for using the same.

The present invention provides a method and apparatus for reducing condensation in a respiratory circuit during a delivery of humidifying agent into the respiratory circuit. A first amount of humidification agent to a first volume of gas is delivered to a patient respiratory circuit during a patient inhalation cycle or immediately after a patient exhalation cycle, and the humidification agent or the first volume of gas is heated. Condensation is removed from the respiratory circuit at least in part by providing, during a patient exhalation cycle or immediately after a patient inhalation cycle, a second amount of the humidification agent to a second volume of gas being delivered from the gas source to the patient respiratory circuit, the second amount of the humidification agent being significantly less than the first amount of the humidification agent.

A dispenser device for fluid or powder, including an air expeller (20) and a reservoir (30). The reservoir (30) has an air inlet (31) connected to the air expeller (20) and a composition outlet (32) connected to a dispenser opening (10), and is removably mounted on the air expeller. After actuation, the empty reservoir can be removed from the air expeller and replaced with a new reservoir. The air inlet (31) is closed by a first closure element (40) and the composition outlet (32) is closed by a second closure element (50). A mechanical opening system (61, 62) co-operates with the first and second closure elements to expel each closure element from the closed position. The mechanical opening system has a first rod (61) secured to the air expeller (20), and a second rod (62) secured to the dispenser head (1), co-operating with a closure element during actuation.

Aspects of the invention include devices, systems, and methods for enhancing a user's sleep. A flexible frame supports a flow manifold which can be used in unison with adjoined or adjacently integrated supportive members utilized to create soft objects of various designs and materials. These types of objects can be in the form of a pillow, mattress topper, even a child's stuff animal and other various stationary and portable soft sided padded embodiments as disclosed in this application. These various designs and embodiments house an integrated flow delivery system which is delivers concentrated, pressurized, and or altered gaseous flowing elements in a controlled and fluidic manner as to help address certain types of sleeping and breathing issues during their resting and sleep states.

An optimization methodology is employed to match vibratory inhaler devices having certain characteristics to the particular anatomical and acoustic properties of a patient's vocal tract, in order to achieve the most effective dispersion of a dry powder medicament using inspiratory effort of a user of the inhaler. In embodiments, optimization involves employing one or more measurements of acoustic frequency spectrum properties as well as one or more anatomical/geometric measurements of the structures comprising the particular patient's mouth, pharynx, and upper respiratory tract and matching a vibratory inhalation device that corresponds thereto.