A method includes receiving, from a primary pressure sensor, a pressure measurement indicative of a pressure of a patient cavity and controlling, by an insufflator, a supply of the insufflation fluid to the patient cavity based on the pressure measurement from the primary pressure sensor. The method further includes delivering, by a trocar, the supplied insufflation fluid to the patient cavity via an access port, wherein: the access port comprises a seal and a retractor; and the access port facilitates access therethrough to the patient cavity.

A collection device (1) for minimising dispersal of pathogens into the environment during insufflating of the peritoneal cavity (12) of a subject (3), and which are entrained in insufflating gases and other gases escaping through an incision (8) in the abdominal wall (9) of the subject (3), through which a trocar is entered into the peritoneal cavity (12) comprises a patch (5) supported on a support framework (30). The patch (5) terminates in an outer peripheral portion (20) with a pressure sensitive adhesive (21) coated thereon for sealably securing the outer peripheral portion (20) to the abdominal wall (9). A central access opening (24) formed in the patch (5) tightly and sealably engages the trocar (10). With the trocar (10) extending through the access opening (24) of the patch (5) and with the patch (5) bonded by the pressure sensitive adhesive (21) to the abdominal wall (9) of the subject, the patch (5) defines with the trocar (10) and the abdominal wall (9) of the subject an annular collection chamber (17) for collecting insufflating and other gases leaking through the opening (8) in the subject. An outlet port (25) extending from the patch (5) and communicating with the collection chamber (17) is connected through a filter (29) to a vacuum system (27) for drawing gases from the collection chamber (17) where they are filtered in the filter (29) for removing pathogens therefrom, and clean filtered gases are dispersed into the atmosphere from the vacuum system (27). Other access devices and apparatus for collecting and filtering insufflating gases and other gases leaking through an incision formed in the body of a subject or through other body orifices are also disclosed.

Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO.sub.2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Plasma delivery tips of medical-grade plasma generating devices are configured to exclude potential contaminants while operating within body cavities. In some embodiments, delivery tips are provided with an antechamber, which is optionally filled by pressure of ionizing gas to prevent contamination. Some embodiments are provided with one or more interior and/or exterior valves configured to prevent proximal ingress of contamination to the longitudinal position of the discharge electrode, or at all into the gas delivery lumen. In some embodiments, an expandable distal section of the plasma delivery tip acts as a valve which seals when closed, and when open expands to generate an inflated antechamber into which plasma is delivered.

A system for delivery of gas to a tissue, comprises: a first container containing the gas, an applicator having a distal end arranged to deliver the gas to the tissue, a second container containing a purging gas; and a flow control system for controlling flow of gas. The system also comprises a three-port valve having a first port for receiving the gas from the first container, a second port for receiving the purging gas from the second container, and a third port in fluid communication with the applicator. The valve is switchable between a first state at which the first port fluidly connects to the third port, and a second state at which the second port fluidly connects to the third port.

A system for monitoring gas composition in a surgical cavity during an endoscopic surgical procedure includes an gas recirculation system including a main gas flow circuit for fluid communication with a surgical cavity. The system includes a sensor for monitoring a gas species in a gas flow from a surgical cavity of a patient. The sensor is positioned in a channel branching off from the main gas flow circuit coming from the surgical cavity.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

A system suitable for delivering a therapeutic agent to a target site may include a container for holding a therapeutic agent; a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container; a catheter in selective fluid communication with the container and configured for delivery of the therapeutic agent or the pressurized fluid to a target site; and a housing configured to securely retain the container and movably support a switch, where the switch is movable between a first position and a second position, where when the switch is in the first position, delivery of the therapeutic agent is prevented while delivery of the pressurized fluid is permitted, and where when the switch is in the second position, delivery of the therapeutic agent is permitted.

A clotting agent delivery system comprises a frame, a passageway extending along the frame, a discharge opening connected to the passageway, a clotting agent reservoir fluidly connected to the passageway to hold a clotting agent substance, a valve in the passageway to control flow of the substance through the passageway, and an actuator to allow propellent to flow into the passageway, wherein the valve and clotting agent reservoir cooperate to provide clotting agent substance to the discharge opening at constant pressure using the propellant. A method for delivering a clotting agent comprises inserting a delivery catheter into an anatomic area, coupling a clotting agent delivery system to the delivery catheter, the clotting agent delivery system having a reservoir of a clotting agent, operating a valve to release propellant for propelling the clotting agent, and conveying the propellant and the clotting agent to the delivery catheter at a constant pressure.

A clotting agent delivery system comprises a frame, a passageway extending along the frame, a discharge opening connected to the passageway, a clotting agent reservoir fluidly connected to the passageway to hold a clotting agent substance, a valve in the passageway to control flow of the substance through the passageway, and an actuator to allow propellent to flow into the passageway, wherein the valve and clotting agent reservoir cooperate to provide clotting agent substance to the discharge opening at constant pressure using the propellant. A method for delivering a clotting agent comprises inserting a delivery catheter into an anatomic area, coupling a clotting agent delivery system to the delivery catheter, the clotting agent delivery system having a reservoir of a clotting agent, operating a valve to release propellant for propelling the clotting agent, and conveying the propellant and the clotting agent to the delivery catheter at a constant pressure.