Provided are systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure source provides negative pressure to a wound dressing and a biasing mechanism provides positive pressure to a fluid reservoir.

An aspiration control device may include a conduit having a distal end and a proximal end and defining a conduit lumen, wherein the conduit defines a vent that is open to the conduit lumen, a coupling configured to couple the proximal end of the conduit with a vacuum source and an inner cannula such that a vacuum is supplied to each of the conduit lumen and the inner cannula, a sleeve movably disposed about the conduit and configured to move relative to the vent to achieve a desired level of vacuum delivered to the inner cannula.

Liquid applicators wherein the applicators include a lever having a hinge, grip and foot integrally formed with a hollow body suitable for receiving a liquid-filled ampoule. The foot is positioned adjacent the ampoule and crushes the ampoule when the lever is depressed.

Methods to provide customized skin care by using specimen dispensing device to dispense specimens from removable dispensers for the purpose of treating skin of a user are presented. Methods to utilize the embedded memory and electrical interface of the dispensing device and dispensers to produce customizable skin care products that give better skin treatment results are also presented. The invention may also be applied to health care and personal care needs.

Pharmaceutical compositions having enhanced active component permeation properties are described.

A double disk dermal device for administration of one or more active agents to the skin or mucosa of a host, in particular a patch is described including: a) active reservoir film layer; b) a backing overlay adjacent to the active reservoir film layer extending beyond the perimeter of the reservoir layer in all directions; c) second overlay backing layer with a coating of pressure sensitive adhesive which is adjacent to the first backing overlay extending beyond the perimeter of the first backing overlay in all directions; and d) a removable release liner. A method of making the device is also provided.

A method and system are provided for managing a skin condition. The method includes determining, using at least one of an image capture device and a temperature sensor, a skin inflammation value. The method further includes determining, by a hardware processor, a risk value associated with an improper determination of the skin inflammation value. The method also includes triggering, by the hardware processor, an action relating to the skin condition based on the skin inflammation value and the risk value.

A sprayable polymeric foam hemostat for both compressible and non-compressible (intracavitary) acute wounds is disclosed. The foam comprises hydrophobically-modified polymers, such as hm-chitosan, or other amphiphilic polymers that anchor themselves within the membrane of cells in the vicinity of the wound. By rapidly expanding upon being released from a canister pressurized with liquefied gas propellant, the foam is able to enter injured body cavities and staunch bleeding. The seal created is strong enough to substantially prevent the loss of blood from these cavities. Hydrophobically-modified polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The amphiphilic polymers form solid gel networks with blood cells to create a physical clotting mechanism that prevent loss of blood.

The present invention is directed to a spray applicator for spraying a tissue treatment medicant onto a tissue that has a container containing the medicant and is positioned at a proximal end of the spray applicator; a spray tip positioned at a distal end of the spray applicator; a cannula connecting the container with the spray tip; an actuatable dispensing mechanism at a proximal end of the applicator to express the medicant from the container through the cannula and through the spray tip toward the tissue; an optional pressurized gas source discharging a gas through the cannula in the vicinity of the spray tip or inside the spray tip; and a distance indicator that provides indicia of the distance between the spray tip and the tissue but does not prevent positioning the spray tip closer to the tissue than a defined distance for the distance indicator.

A liquid dispensing applicator that can include a sound-generating system for generating a sound during rotation of the container body to indicate to a user that the rotation is performed. The sound-generating system includes at least one knob and a plurality of ribs. The at least one knob cooperates with at least some of the ribs during rotation of the container body, in order to generate the sound. The liquid dispensing applicator can alternatively or also include a wing element insertable into a slot provided in an absorbent material. The wing element extends from an outer surface of the head component and comprises opposing surfaces and a at least one edge spike provided on an edge of the at least one wing element, and configured to prevent the absorbent material from being removed after insertion of the wing element into the slot.