The invention relates to a coupling component for a fluid coupling (1) for releasably connecting fluid-conveying components, in particular fluid-conveying components in medical equipment, wherein the coupling component comprises a coupling housing (14) through which a fluid channel (17) passes in regions and which is provided with a coupling recess (7) that is sunken into a surface (15) of the coupling housing (14), wherein a channel opening (18) of the fluid channel (17) ends at an end face (19) of the coupling recess (7). According to the invention, it is provided that the channel opening (18) is covered by a membrane seal (4) which is made of a resilient material and through which a fluid gap passes (8) that is designed such that the membrane seal (4), when in a resting position, seals the channel opening (18) and, when in an operative position, opens the channel opening (18), wherein at least one yielding depression (29) is formed in the coupling recess (7) adjacently to the channel opening (18), which depression is designed for an yielding movement of a region (36, 37) of the membrane seal (4) when the membrane seal (4) transitions from the resting position into the operative position.

An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution (“IVSS”). The drug product is transferred to the prefilled delivery container via a delivery container adapter.

An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution (“IVSS”). The drug product is transferred to the prefilled delivery container via a delivery container adapter.

Disclosed herein are approaches of forming a component, such as a valve, for a medical device. One approach includes providing a cylinder within a tube, the tube and the cylinder joined together in an interference fit, and annealing the tube and the cylinder, wherein the tube and the cylinder are no longer joined together in the interference fit following the annealing.

In various embodiments, a surgical instrument for use with a robotic surgical system is disclosed. The surgical instrument comprises a mounting portion, an elongate shaft, and an end effector. The end effector comprises a first jaw, a second jaw, a staple cartridge, a closure member, a drive screw, a thrust bearing, a coupling member, and a sled. The closure member is configured to move the second jaw from an open position toward a closed position in response to an output motion. The drive screw is configured to apply a distal force to the coupling member when the drive screw is rotated. The coupling member is configured to engage the second jaw and retain the second jaw at a distance relative to the first jaw during a firing stroke. The sled ejects staples from the staple cartridge when the sled is moved by the coupling member during the firing stroke.

A system for adapting a tubular surgical device for grasping by a surgical instrument is provided that has a distal portion, an adaptor positioned proximally and configured to be disposed about or within a lumen of the tubular surgical device, which has an effective durometer to resist crushing by the surgical instrument. In some embodiments, the adaptor is configured with an external diameter greater than the internal diameter of the lumen of the tubular surgical device. In some embodiments, the adaptor is configured with an external diameter less than or equal to the internal diameter of the tubular surgical device.

A system for adapting a tubular surgical device for grasping by a surgical instrument is provided that has a distal portion, an adaptor positioned proximally and configured to be disposed about or within a lumen of the tubular surgical device, which has an effective durometer to resist crushing by the surgical instrument. In some embodiments, the adaptor is configured with an external diameter greater than the internal diameter of the lumen of the tubular surgical device. In some embodiments, the adaptor is configured with an external diameter less than or equal to the internal diameter of the tubular surgical device.

A catheter system includes abase plate having a bottom surface, an outer circumferential wall, a circular flange extending inwardly from the outer circumferential wall, and an inner ring that is spaced apart from the outer circumferential wall, extends upwardly from the bottom surface, and defines a central opening in the base plate. A catheter is placed within the central opening of the base plate. A cover is placed over and secured to the base plate. The cover has a closed upper portion defining an internal chamber of the cover and a lower portion defining an opening in the cover. The lower portion includes a skirt with a flange extending outwardly around a periphery of the skirt to engage the circular flange of the base plate and form a closed reservoir. Methods of accessing cerebrospinal fluid using the catheter systems are also provided.

A stapling assembly comprising a first jaw, a second jaw, an elongate channel configured to receive a staple cartridge, a firing member, a biasing member, and a lock member movable between locked and unlocked positions is disclosed. One of the first jaw and the second iaw is movable relative to the other of the first jaw and the second jaw between an open position and a closed position. The staple cartridge comprises staples and a sled configured to be advanced by the firing member during a firing stroke. The firing member comprises a cutting edge, a first camming member configured to engage the first jaw during the firing stroke, and a second camming member configured to engage the second jaw during the firing stroke. The firing member is prevented from performing the firing stroke when the stapling assembly is in one of a plurality of lockout states.

A punching device, for punching a lumen and implanting an implant device, includes at least the implant device for punching the lumen and for implantation into the lumen. In addition, the punching device includes an implantation device, a closure device, and an actuation device.