A method of generating a customized headgear that includes a plurality of physical features and being usable with a mask component that supplies a flow of breathing gas to the patient's airways. The method includes receiving one or more parameters pertaining to the patient's head, subjecting at least some of the parameters to one or more algorithms to determine at least one of a length of a physical feature of the plurality of physical features and an angle between a pair of physical features of the plurality of physical features, generating an outline of at least a portion of a body which, when formed, is usable to assemble therefrom at least a portion of the headgear, and outputting a pattern usable to enable the formation of the at least portion of the body from at least a first sheet of at least a first material.

The invention relates to a method of determining a permeation property of hollow-fibre membranes wherein the permeation property of the hollow-fibre membrane is determined on a hollow-fibre membrane bundle which has been introduced into a housing and has terminally open hollow-fibre membranes at a first end of the hollow-fibre membrane bundle and terminally closed hollow-fibre membranes at a second end of the hollow-fibre membrane bundle. The invention more particularly relates to a method of determining the ultrafiltration rate and/or the ultrafiltration coefficient of hollow-fibre membranes.

A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.

A method of adapting an auto injector configured to actuate a prefilled syringe, the auto injector having a biasing member having a spring constant, the prefilled syringe being filled with a volume of therapeutic fluid, the prefilled syringe including a barrel, stopper, and a needle, the stopper having a path of travel, the biasing member arranged to move the stopper along the path of travel. An auto injector having an injection spring adapted to an aged prefilled syringe.

A system is provided for generating a custom article to fit a target surface. During operation, the system compares an input dataset with a number of cut template cut meshes. A respective cut template cut mesh includes one or more cutting paths that correspond to a boundary of the mesh. Next, the system identifies a template cut mesh that produces a closest match with the input dataset, and applies global geometric transformations to the identified template cut mesh to warp the template cut mesh to conform to the input dataset. The system further refines and projects a set of boundary and landmark points from the template cut mesh to the input dataset to define cutting paths for the input dataset. Next, the system applies cutting paths to the input dataset to produce a cut-and-trimmed mesh.

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

A valve island for a hydraulic assembly and a hydraulic assembly featuring a valve island. The valve island and the hydraulic assembly are used with a dialysis machine. The valve island has a main part in which at least one fluid flow duct is formed. The main part is produced by additive manufacturing or injection molding. The hydraulic assembly includes a support on which at least one valve island is arranged directly or indirectly.

A protective sleeve (100) is provided for vape fluid cartridges or ampules (130). Open ends (103, 104) facilitate insertion of a vape fluid cartridge (130). One or more apertures (120A, 120B) may be provided to permit viewing of cartridge fluid level. The sleeve (100) may be formed from an elastic material, such as silicone. An elevated section (110) may be provided to inhibit rolling and/or permit ornamentation.

A dressing includes a drape, a metal coating provided on a skin-facing surface of the drape, a pressure-sensitive adhesive provided on a lower surface of the metal coating, and a gasket having a frame shape. The drape is a thin film. The gasket includes an inner edge defining an opening and an outer edge offset inwardly from an outer periphery of the drape. The gasket is in contact with the metal coating and leaves a margin of pressure-sensitive adhesive around the gasket.

A breathing assistance apparatus has a pressurised gases source featuring a lightweight impeller with a plastic shaft. The impeller is shroudless. The plastic shaft is supported within the stator by a bearing structure. The resilient motor mount couples the stator and the housing and provides compliance and/or damping for the motor.