A method and system of adaptive cold atmospheric based treatment for diseased tissues, such as an area with cancerous cells, is disclosed. A plasma device generates a cold atmospheric plasma jet directed at the area having cancerous cells. A sensor is operable to sense the viability of the cancerous cells in the area. A controller is coupled to the plasma device and sensor. The controller is operative to control an initial plasma jet generated by the plasma device. The controller receives a sensor signal from the sensor to determine cell viability of the selected cells from the initial plasma jet. The controller adjusts the plasma jet based on the viability of the cancerous cells.

A method and system of adaptive cold atmospheric based treatment for diseased tissues, such as an area with cancerous cells, is disclosed. A plasma device generates a cold atmospheric plasma jet directed at the area having cancerous cells. A sensor is operable to sense the viability of the cancerous cells in the area. A controller is coupled to the plasma device and sensor. The controller is operative to control an initial plasma jet generated by the plasma device. The controller receives a sensor signal from the sensor to determine cell viability of the selected cells from the initial plasma jet. The controller adjusts the plasma jet based on the viability of the cancerous cells.

The device includes an outer conductor and an inner conductor arranged approximately coaxial with each other. The outer conductor surrounds the inner conductor. The outer conductor and the inner conductor are arranged and configured to generate an electromagnetic field with lines of force extending from a front surface of the inner conductor to a front surface of the outer conductor. The device further includes an energy delivery window arranged in front of the outer conductor and the inner conductor.

The present specification discloses a pulsed electromagnetic field system having planar microcoil arrays integrated into clothing. Each of the planar microcoil arrays has two or more planar microcoils positioned on a flexible substrate. The planar microcoil arrays are connected to a controller configured to generate an electrical current and transmit that electrical current, in accordance with a particular stimulation protocol, to each of the planar microcoil arrays.

Body wearable treatment apparatus for treatment of neurological disorders and conditions of the central nervous system by application of electromagnetic fields thereto, the apparatus including a coil mounting portion and a body mounting portion, the coil mounting portion being removably mounted on the body mounting portion and a system including at least one database storing information relating to treatment protocols, a server communicating with the at least one database and body wearable treatment apparatus communicating with the server, the body wearable treatment apparatus including a coil mounting portion and a body mounting portion, the coil mounting portion being removably mounted on the body mounting portion.

A system includes ultrasound transducers configured to generate and direct ultrasound beams at a region within a portion of a subject's brain, sensors configured to measure a response from the portion of the subject's brain in response to one or more ultrasound beams, and an electronic controller in communication with the ultrasound transducers configured to generate, based on a measured response from the portion of the subject's brain in response to two or more ultrasound beams generated from two or more different angles, a model of the portion of the subject's brain, wherein the model has a higher resolution than a maximum resolution of a single ultrasound beam, and generate, based on the model of the portion of the subject's brain, stimulation parameters for the ultrasound transducers to generate and direct a stimulation ultrasound beam at the region within the portion of the subject's brain.

A method and apparatus for treating pre-ulcerative lesions is disclosed. In some embodiments, pre-ulcerative lesions, which may include unerupted diabetic foot ulcers, unerupted pressure ulcers, and venous leg ulcers, may be detected and located prior to ulceration. A high-power pulsed electromagnetic field therapy may be provided to the location of the pre-ulcerative lesion.

An apparatus and method configured to control a brain stimulation device. The apparatus and method include a brain stimulation apparatus including, an input unit configured to receive at least one biological metric measurement value of a user, a neural network unit configured to determine a treatment pulse frequency equal to a weighted sum of the at least one biological metric measurement value of the user, wherein the weighted sum includes a plurality of weighting factors corresponding to each of the at least one biological metric measurement values, and wherein the plurality of weighting factors are determined based on optimized outcome results from previous administered treatments using treatment pulse frequencies determined by previous weighting factors, and a control unit configured to control a motor to operate at the treatment pulse frequency determined.

Methods for treating and managing pain in a patient with therapeutic neuromodulation and associated systems and methods are disclosed herein. Chronic or debilitating pain can be associated, for example, with a disease or condition of the abdominal or reproductive viscera. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a target blood vessel of a diseased or damaged organ of a patient experiencing pain. Targeted sympathetic nerve activity can be modulated at least along afferent pathways which can improve a measurable parameter associated with the pain of the patient The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

A method for directing therapeutic nanoparticle-labeled cells to selected locations within the body and/or for retaining therapeutic nanoparticle-labeled cells at selected locations within the body, the method comprising: providing an article comprising a body of material configured to be secured about the body of a patient and having a plurality of pockets thereon, wherein each pocket is sized to receive and retain one or more magnets therein; injecting therapeutic USPIO nanoparticle-containing cells into a target therapy site; securing the article to the body of the patient; and inserting at least one magnet into at least one pocket so as to provide a desired magnetic field for further directing therapeutic nanoparticle-labelled cells to a target therapy site and/or for retaining therapeutic nanoparticle-labeled cells at the target therapy site.