A61P39/00

Combination Drugs of Lachnospiraceae Bacteria and Human Immunoglobulin
20220347233 · 2022-11-03 ·

A combined drug contains Lachnospiraceae bacteria and human immunoglobulin (HIg). HIg has a therapeutic effect on radiation injuries, and the combination of Lachnospiraceae bacteria and HIg can further improve this therapeutic effect. The combination drug can be administered to patients who were undergoing radiotherapy and to people who accidentally receive excessive irradiation.

COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES

Compositions and methods for protecting insect pollinators against the harmful cognitive effects of pesticides are disclosed. The compositions are suitable for administration to or ingestion by an insect pollinator and contain one or more phenolic compounds, such as the flavonoids quercetin, rutin, kaempferol and p-coumaric acid in an effective amount to protect against pesticide-induced impairment of a cognitive function of the insect pollinator. Methods of using such compositions for preventing or reducing pesticide-induced impairment of cognitive functions including learning, memory, decision-making, motor activity, and navigation in an insect pollinator are also provided. The compositions and methods protect insect pollinators including honeybees and bumblebees against neurotoxic pesticides with different pharmacodynamics including neonicotinoids, such as Imidacloprid, fipronil, and pyrethroids, such as deltamethrin.

Synthetic receptors for ionophoric compounds

The present invention relates to synthetic receptors for ionophoric compounds, such as ionophoric toxins. Hence, the invention provides synthetic molecules capable of binding different ionophoric compounds, thereby being suitable for use in the detection, isolation and detoxification of such ionophoric compounds. The present invention further provides the use of such synthetic receptors in human and veterinary medicine, such as in the diagnosis, prevention and/or treatment of disorders caused by such ionophoric compounds. Finally, the invention provides methods of preparing such synthetic receptors for ionophoric compounds.

Apoaequorin and Curcumin Containing Compositions and Methods
20230078821 · 2023-03-16 ·

Compositions containing apoaequorin and curcumin and methods for their use in treating symptoms and disorders, for example, mental disorder, anxiety, cognitive function, sleep quality, energy quality, mood quality, memory quality or pain are provided by the present invention.

Apoaequorin and Curcumin Containing Compositions and Methods
20230078821 · 2023-03-16 ·

Compositions containing apoaequorin and curcumin and methods for their use in treating symptoms and disorders, for example, mental disorder, anxiety, cognitive function, sleep quality, energy quality, mood quality, memory quality or pain are provided by the present invention.

Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof

The disclosure relates to the treatment of primary and metastatic cancer using radiation. Specifically, the disclosure relates to methods providing for the selective accretion of cytoprotective agent in tissues and/or organs, sensitive to radiation that are adjacent to malignant tumors prior to radiation of the tumors at a dose that otherwise would be toxic to the tissues and/or organs, but are necessary to achieve ablative outcome on the tumors.

Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof

The disclosure relates to the treatment of primary and metastatic cancer using radiation. Specifically, the disclosure relates to methods providing for the selective accretion of cytoprotective agent in tissues and/or organs, sensitive to radiation that are adjacent to malignant tumors prior to radiation of the tumors at a dose that otherwise would be toxic to the tissues and/or organs, but are necessary to achieve ablative outcome on the tumors.

COMPOSITION AND APPLICATION THEREOF IN PREPARING PRODUCT FOR PROTECTING MITOCHONDRIA
20230072134 · 2023-03-09 ·

The invention relates to the field of health food technologies, and particularly to a composition and an application thereof in preparing a product for protecting mitochondria. The invention provides a composition, the raw materials of which include Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris and nicotinamide. The composition has the effects of improving an oxidative stress level under a mitochondrial dysfunction and delaying mitochondrion-related aging. Compared with a single constituent, constituents in the composition cooperate with each other to produce a synergistic effect, which significantly improves an effect of protecting a mitochondrial function.

COMPOSITION AND APPLICATION THEREOF IN PREPARING PRODUCT FOR PROTECTING MITOCHONDRIA
20230072134 · 2023-03-09 ·

The invention relates to the field of health food technologies, and particularly to a composition and an application thereof in preparing a product for protecting mitochondria. The invention provides a composition, the raw materials of which include Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris and nicotinamide. The composition has the effects of improving an oxidative stress level under a mitochondrial dysfunction and delaying mitochondrion-related aging. Compared with a single constituent, constituents in the composition cooperate with each other to produce a synergistic effect, which significantly improves an effect of protecting a mitochondrial function.

Sporoderm-removed <i>Ganoderma lucidum </i>spore powder, granule and preparation method thereof

The present invention discloses sporoderm-removed Ganoderma lucidum spore powder, granule and a preparation method thereof. The sporoderm-removed Ganoderma lucidum spore powder and granule is obtained from sporoderm-disrupted Ganoderma lucidum spore powder through extraction, centrifugation, sporoderm removal, concentration, drying, and pulverization; and in the sporoderm-removed Ganoderma lucidum spore powder and granule, the content of polysaccharides is 10-20 g/100 g, and the content of total triterpenes is 4-10 g/100 g. The present invention has beneficial effects of enhancing immunity and having an auxiliary protection function against radiation hazards. The content of active components is increased by processing the sporoderm-disrupted Ganoderma lucidum spore powder through a special process, such that the human body can more effectively absorb the nutritional components contained in the Ganoderma lucidum spores, and thus the Ganoderma lucidum spore powder gives play to its efficacy better while it is convenient to carry and take the Ganoderma lucidum spore powder.