The present invention relates to a pharmaceutical composition comprising piperonylic acid as an effective ingredient for anti-aging or regenerating the skin. A composition according to the present invention utilizes piperonylic acid that various plant species naturally contain therein and thus does not cause side effects. Piperonylic acid activates signals associated with cell survival, growth, and proliferation to exhibit the effect of increasing the resistance and survival of skin cells against external stimuli and enhancing the regeneration of the skin damaged due to external stimuli or senescence. In addition, piperonylic acid of the present invention has a similar function to EGF, but is stable and small in size in contrast to EGF. Thus, piperonylic acid of the present invention has the advantage of being able to easily move to the skin basal layer across the skin barrier and perform its function. Piperonylic acid of the present invention is expected to find applications in various fields including medicines, quasi-drugs, cosmetics, cosmetic substances, functional biomaterials, and functional food materials. In addition, the present invention provides a use of piperonylic acid for preventing hair loss or promoting hair growth. Piperonylic acid is a component derived from natural products, is safe, has few side effects, and has an effect of effectively improving androgenic alopecia symptoms, and the like, and thus can be used in various applications such as a cosmetic, drug, quasi-drug or food for preventing hair loss or promoting hair growth.

The present invention relates to a pharmaceutical composition comprising piperonylic acid as an effective ingredient for anti-aging or regenerating the skin. A composition according to the present invention utilizes piperonylic acid that various plant species naturally contain therein and thus does not cause side effects. Piperonylic acid activates signals associated with cell survival, growth, and proliferation to exhibit the effect of increasing the resistance and survival of skin cells against external stimuli and enhancing the regeneration of the skin damaged due to external stimuli or senescence. In addition, piperonylic acid of the present invention has a similar function to EGF, but is stable and small in size in contrast to EGF. Thus, piperonylic acid of the present invention has the advantage of being able to easily move to the skin basal layer across the skin barrier and perform its function. Piperonylic acid of the present invention is expected to find applications in various fields including medicines, quasi-drugs, cosmetics, cosmetic substances, functional biomaterials, and functional food materials. In addition, the present invention provides a use of piperonylic acid for preventing hair loss or promoting hair growth. Piperonylic acid is a component derived from natural products, is safe, has few side effects, and has an effect of effectively improving androgenic alopecia symptoms, and the like, and thus can be used in various applications such as a cosmetic, drug, quasi-drug or food for preventing hair loss or promoting hair growth.

An improved composition of hair oil for stimulation of hair growth, control of hair fall, dandruff and infections thereof. The composition of hair oil comprising active ingredients of variety of herbs, vitamins, essential oils and Organic Jojoba. The composition of hair oil supports the hair growth and relaxation of the scalp. The composition of hair oil also effectively reduces/remove dandruff and thereby control hair fall in the subject (e.g., not limiting to male/female human). The composition of hair oil additionally demonstrates the properties of cooling effect, darkening of hair and promotion of hair upon continuous use of the hair oil by the subjects.

An improved composition of hair oil for stimulation of hair growth, control of hair fall, dandruff and infections thereof. The composition of hair oil comprising active ingredients of variety of herbs, vitamins, essential oils and Organic Jojoba. The composition of hair oil supports the hair growth and relaxation of the scalp. The composition of hair oil also effectively reduces/remove dandruff and thereby control hair fall in the subject (e.g., not limiting to male/female human). The composition of hair oil additionally demonstrates the properties of cooling effect, darkening of hair and promotion of hair upon continuous use of the hair oil by the subjects.

A method and composition for promoting hair growth comprises an oil solution created with predetermined quantities of certain oils such as sesame oil, avocado oil, sweet almond oil, coconut oil, and ricinus oil. A blended final product is created by adding predetermined quantities of certain plants to the oil solution, such as parsley and aloe vera. The final product is heated and applied to a surface for hair growth. After a certain amount of time it is washed off the surface for hair growth. These steps are repeated daily for a full course of treatment, which comprises a few weeks. The course may be repeated about every other month.

A method and composition for promoting hair growth comprises an oil solution created with predetermined quantities of certain oils such as sesame oil, avocado oil, sweet almond oil, coconut oil, and ricinus oil. A blended final product is created by adding predetermined quantities of certain plants to the oil solution, such as parsley and aloe vera. The final product is heated and applied to a surface for hair growth. After a certain amount of time it is washed off the surface for hair growth. These steps are repeated daily for a full course of treatment, which comprises a few weeks. The course may be repeated about every other month.

A layered solid formulation (100a) as one hydrogen supply material (200) according to the present invention includes silicon fine particles having a capability of generating hydrogen and aggregates of the silicon fine particles, and a physiologically acceptable medium (90b) that gets contact with the silicon fine particles or the aggregates thereof. The hydrogen supply material (200) is a hydrogen supply material for bringing the hydrogen into contact with the skin and/or the mucous membrane through the medium (90b).

A layered solid formulation (100a) as one hydrogen supply material (200) according to the present invention includes silicon fine particles having a capability of generating hydrogen and aggregates of the silicon fine particles, and a physiologically acceptable medium (90b) that gets contact with the silicon fine particles or the aggregates thereof. The hydrogen supply material (200) is a hydrogen supply material for bringing the hydrogen into contact with the skin and/or the mucous membrane through the medium (90b).

The present invention is a hair oil developed with the hair care needs of African American women in mind. The invention is comprised of sweet almond oil, carrot oil, frankincense oil, cedarwood oil, orange oil, saffron oil, gingko oil, amla oil, neem oil, karanja oil, fo-ti oil, ginseng oil, green tea oil, onion seed oil, lemongrass oil, geranium oil, hyssop oil, clary sage, nettle leaf oil, myrrh oil, and chamomile oil.

Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.