An oral appliance, a method of making the oral appliance for delivering an antimicrobial composition to an oral cavity and a method of treatment are provided. The oral appliance has an exterior surface and an interior surface, the interior surface of the oral appliance configured to contour at least a portion of teeth and/or soft tissue areas of the oral cavity. The antimicrobial is dispensed by itself or as a composition in a carrier at discrete regions of the interior surface, the exterior surface or both the interior surface and the exterior surface of the oral appliance for delivering the antimicrobial or an antimicrobial composition to the oral cavity, wherein the antimicrobial is present in the carrier in an amount of about 0.01% to about 20% w/w, v/v or w/v based on a total weight or a total volume of the carrier.

Disclosed are controlled release particles including: (a) a flavor oil; (b) a plant derived fat; (c) a plant derived wax; (d) a plant derived surfactant; and (e) optionally an anti-oxidant. The particles are particularly useful as a flavor delivery system of a personal care product, an oral care product, a powdered food product, a fluid food product, a powdered nutritional supplement, a fluid nutritional supplement, a bakery dough, a dairy product, a savory food product, a noodle bowl and a non-animal based meat analogue.

Disclosed are controlled release particles including: (a) a flavor oil; (b) a plant derived fat; (c) a plant derived wax; (d) a plant derived surfactant; and (e) optionally an anti-oxidant. The particles are particularly useful as a flavor delivery system of a personal care product, an oral care product, a powdered food product, a fluid food product, a powdered nutritional supplement, a fluid nutritional supplement, a bakery dough, a dairy product, a savory food product, a noodle bowl and a non-animal based meat analogue.

Provided is a multi-component system, and a method for preparing a hypochlorite composition with increased viscosity with a composition pH in the range of 7 to 12. For example, and preferably, the system and method may be used to provide a (hydro)gelled hypochlorite composition. The system or method makes use of a first quantity of a first component including hypochlorite or a source of hypochlorite at a pH in the range of 10 to 13.5 preferably 11 to 13.5 and a separate component including a pH induced thickening agent in “dry” form or in dissolved and/or dispersed form at a pH less than 7. The pH induced thickener is capable of increasing the viscosity of a composition upon subjecting it to an increasing pH such as in particular the composition pH in the range of 7 to 12. The pH induced thickener is thus for causing an increase of viscosity in the hypochlorite composition caused by the alkaline composition pH experienced by the pH induced thickener. A pH adjusting (acidic or basic) agent may be present to adjust the composition pH to the desired range. The hypochlorite composition is obtainable by combining amounts of the components in the system.

Provided is a multi-component system, and a method for preparing a hypochlorite composition with increased viscosity with a composition pH in the range of 7 to 12. For example, and preferably, the system and method may be used to provide a (hydro)gelled hypochlorite composition. The system or method makes use of a first quantity of a first component including hypochlorite or a source of hypochlorite at a pH in the range of 10 to 13.5 preferably 11 to 13.5 and a separate component including a pH induced thickening agent in “dry” form or in dissolved and/or dispersed form at a pH less than 7. The pH induced thickener is capable of increasing the viscosity of a composition upon subjecting it to an increasing pH such as in particular the composition pH in the range of 7 to 12. The pH induced thickener is thus for causing an increase of viscosity in the hypochlorite composition caused by the alkaline composition pH experienced by the pH induced thickener. A pH adjusting (acidic or basic) agent may be present to adjust the composition pH to the desired range. The hypochlorite composition is obtainable by combining amounts of the components in the system.

The invention relates to the use of a powder in a powder jet device for cleaning tooth surfaces by powder spraying, wherein the powder comprises rhamnose and/or arabinose. The invention also relates to a process for cleaning tooth surfaces with a powder jet device, wherein a powder comprising rhamnose and/or arabinose is used.

The invention relates to the use of a powder in a powder jet device for cleaning tooth surfaces by powder spraying, wherein the powder comprises rhamnose and/or arabinose. The invention also relates to a process for cleaning tooth surfaces with a powder jet device, wherein a powder comprising rhamnose and/or arabinose is used.

This disclosure relates to uses of deoxycholic acid, salts, or derivatives thereof in managing bacterial infections and compositions related thereto. In certain embodiments, this disclosure relates to methods of treating or preventing a bacterial infection comprising administering an effective amount of a deoxycholic acid, salts, or derivatives thereof to a subject in need thereof. In certain embodiments, this disclosure relates to methods of treating or preventing Streptococcus pneumoniae comprising administering an effective amount of a deoxycholic acid salt to a subject in need thereof.

An oral care composition with gum health compound, amino acid, and/or mucoadhesive compound. An oral care composition with gum health compound, a pentapeptide, such as palmitoyl KTTKS, and/or a mucoadhesive compound. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.

An oral care composition with gum health compound, amino acid, and/or mucoadhesive compound. An oral care composition with gum health compound, a pentapeptide, such as palmitoyl KTTKS, and/or a mucoadhesive compound. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.