The present invention is a cosmetic containing a silicone resin whose constitutional units consist of general formulae (A) (R.sup.1.sub.3SiO.sub.1/2)a, (B) (R.sup.2.sub.2SiO.sub.2/2)b, (C) (R.sup.3SiO.sub.3/2) c, and (D) (SiO.sub.4/2) d, where R.sup.1, R.sup.2, and R.sup.3 each independently represent a group selected from an alkyl group having 1 to 8 carbon atoms, an aryl group having 6 to 12 carbon atoms, and a fluorine-substituted alkyl group having 1 to 8 carbon atoms, “a” has a value of 0.2 to 0.5, “b” has a value of 0.0 to 0.1, “c” has a value of 0.2 to 0.6, “d” has a value of 0.2 to 0.5, a+b+c+d has a value of 1.0, a/(c+d) has a value of 0.3 to 0.9, and c/d has a value of 0.4 to 3.0, the silicone resin having a weight-average molecular weight of more than 20000 and 100000 or less. An object of the present invention is to provide accordingly a cosmetic that has no stickiness upon application, has excellent cosmetic durability, and can prevent adhesion to clothes or the like (secondary adhesion).

The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I.sub.2) and an acceptable source of iodate (IO.sub.3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.) for various surfaces and solutions including living and inanimate surfaces and are particularly useful because of their low cost, their reduced use of iodine, their activity (because of the high concentration of free molecular iodine in solution), their reduced environmental impact, their long term storage stability and their reduced toxicity. They also have particular utility in treating food surfaces to retard spoilage, increase useful shelf-life and minimize the human and economic cost of food waste. The compositions inactivate viruses, bacteria (both gram negative and positive), spores and fungi. Compositions according to the present invention may be used and stored in a variety of materials, given the substantial absence of corrosion (non-corrosive) these compositions display. Dental compositions (e.g. preprocedure rinses and other compositions) and methods related thereto are also disclosed.

The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I.sub.2) and an acceptable source of iodate (IO.sub.3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.) for various surfaces and solutions including living and inanimate surfaces and are particularly useful because of their low cost, their reduced use of iodine, their activity (because of the high concentration of free molecular iodine in solution), their reduced environmental impact, their long term storage stability and their reduced toxicity. They also have particular utility in treating food surfaces to retard spoilage, increase useful shelf-life and minimize the human and economic cost of food waste. The compositions inactivate viruses, bacteria (both gram negative and positive), spores and fungi. Compositions according to the present invention may be used and stored in a variety of materials, given the substantial absence of corrosion (non-corrosive) these compositions display. Dental compositions (e.g. preprocedure rinses and other compositions) and methods related thereto are also disclosed.

Storage stable organopolysiloxane gels, preparable in commercial quantities are prepared by the hydrosilylation reaction of a silicone resin containing a hydrosilyatable group, a short chain Si—H-functional silicone, and a long chain Si—H-functional silicone.

This disclosure relates to pentagalloyl glucose compositions and uses in managing microbial infections and compositions related thereto. In certain embodiments, this disclosure relates to compositions of pentagalloyl glucose. In certain embodiments, this disclosure relates to methods of treating or preventing a microbial infection, e.g., an antimicrobial resistant microbial infection, comprising administering to a subject in need thereof an effective amount of pentagalloyl glucose or salt thereof. In certain embodiments, the microbe is bacteria or fungi resistant to one or more antibiotic agents or antifungal agents.

This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each independently represent a hydrogen atom or a methyl group, and R.sup.5, R.sup.6, R.sup.7 and R.sup.8 each independently represent a hydrogen atom, a methyl group or —O—R.sup.9—OH (in the formula, R.sup.9 represents an alkylene group optionally having a substituent group), provided that at least one group of R.sup.5, R.sup.6, R.sup.7 and R.sup.8 is —O—R.sup.9—OH. ##STR00001##

This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each independently represent a hydrogen atom or a methyl group, and R.sup.5, R.sup.6, R.sup.7 and R.sup.8 each independently represent a hydrogen atom, a methyl group or —O—R.sup.9—OH (in the formula, R.sup.9 represents an alkylene group optionally having a substituent group), provided that at least one group of R.sup.5, R.sup.6, R.sup.7 and R.sup.8 is —O—R.sup.9—OH. ##STR00001##

An object of the present invention is to provide a deodorant composition that can chemically deodorize and remove a nitrogen-based malodor of ammonia, amines, or the like, a sulfur-based malodor of mercaptans, sulfides, or the like, and an acid-based malodor of lower fatty acids or the like, and can allow a user to get a fresh feeling sensuously and can impart a fresh feeling. The present invention relates to a deodorant composition containing dihydrocitronellal and hydroxycitronellal.

Disclosed is a composition including controlled release particles, wherein each of the controlled release particles includes: (a) a core including at least one hydrophobic active ingredient; and (b) a wall at least partially surrounding the core and including the reaction products of: (i) an organofunctional silane; (ii) an epoxy; (iii) an amine; (iv) an isocyanate; (v) an epoxide curing agent; wherein the controlled release particles are effective to retain the at least one hydrophobic active ingredient upon exposure to water and effective to release the at least one hydrophobic active ingredient in response to friction. A method for preparing the composition is also disclosed.

Disclosed is a composition including controlled release particles, wherein each of the controlled release particles includes: (a) a core including at least one hydrophobic active ingredient; and (b) a wall at least partially surrounding the core and including the reaction products of: (i) an organofunctional silane; (ii) an epoxy; (iii) an amine; (iv) an isocyanate; (v) an epoxide curing agent; wherein the controlled release particles are effective to retain the at least one hydrophobic active ingredient upon exposure to water and effective to release the at least one hydrophobic active ingredient in response to friction. A method for preparing the composition is also disclosed.