The invention relates to a novel stabilized and solubilized topical formulation for cosmetic improvements and methods of making the same comprising multiplexed molecular penetration enhancers and essential and semi-essential amino acid protein binders for the topical application and transdermal delivery of one or more active ingredients and/or pharmaceutical agents. The invention further relates to the use of the topical formulation in connection with the providing of cosmetic improvements in individuals.

The invention relates to a novel stabilized and solubilized topical formulation for cosmetic improvements and methods of making the same comprising multiplexed molecular penetration enhancers and essential and semi-essential amino acid protein binders for the topical application and transdermal delivery of one or more active ingredients and/or pharmaceutical agents. The invention further relates to the use of the topical formulation in connection with the providing of cosmetic improvements in individuals.

The present invention relates to an anhydrous composition in aerosol form comprising, in particular in a physiologically acceptable medium: a) an oily phase comprising i) at least one volatile oil, and ii) at least one nonvolatile hydrocarbon-based oil, and iii) at least one phenyl silicone, and b) at least one antiperspirant active agent chosen from aluminum and/or zirconium salts or complexes, c) at least one water-insoluble film-forming block ethylenic polymer d) at least one propellant.

The invention also relates to a cosmetic process for treating human perspiration, and optionally the body odors associated with human perspiration, especially underarm odors, comprising the application of said composition to a surface of the skin.

The present invention relates to an anhydrous composition in aerosol form comprising, in particular in a physiologically acceptable medium: a) an oily phase comprising i) at least one volatile oil, and ii) at least one nonvolatile hydrocarbon-based oil, and iii) at least one phenyl silicone, and b) at least one antiperspirant active agent chosen from aluminum and/or zirconium salts or complexes, c) at least one water-insoluble film-forming block ethylenic polymer d) at least one propellant.

The invention also relates to a cosmetic process for treating human perspiration, and optionally the body odors associated with human perspiration, especially underarm odors, comprising the application of said composition to a surface of the skin.

Particles are prepared in an emulsion using a method that includes providing a first reactant having at least two unsaturated carbon-carbon moieties and a second reactant having at least two Si—H moieties, so long as at least one of the unsaturated carbon-carbon moieties of the first reactant or the Si—H moieties of the second reactant is pendant. The method also includes providing a third reactant having a silicon atom and a condensable reactive group bonded to the silicon atom and also having an unsaturated carbon-carbon moiety and/or a Si—H moiety, providing a hydrosilylation catalyst, and providing a polar liquid. The method further includes combining the first, second, and third reactants to form particles that have a cross-linked network wherein the condensable reactive group is disposed on the particles, and adding a silane having an organic moiety and a condensation leaving group to form the particles.

Described herein, are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na.sub.5P.sub.3O.sub.10), and external personal care compositions comprising the complexes, and uses thereof.

Described herein, are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na.sub.5P.sub.3O.sub.10), and external personal care compositions comprising the complexes, and uses thereof.

Disclosed are: (a) controlled release matrix particles containing 10-70 wt. % of a hydrophobic active ingredient, 21-72 wt. % of a polysaccharide, 3.80-12 wt. % of a crosslinking agent, 1.00-6 wt. % of a catalyst and 0.10-5 wt. % of a silica flow aid; (b) controlled release core/shell particles containing 10-70 wt. % of a hydrophobic active ingredient, 1.0-3.2 wt. % of an epoxidized oil, 21-64 wt. % of a polysaccharide, 7.6-23% of an amine-functionality containing material, and 0.10-5 wt. % of a silica flow aid; and (c) hybrid particles wherein the core/shell particles are contained in a matrix. Also disclosed are methods for making the particles and compositions containing the particles.

Disclosed are: (a) controlled release matrix particles containing 10-70 wt. % of a hydrophobic active ingredient, 21-72 wt. % of a polysaccharide, 3.80-12 wt. % of a crosslinking agent, 1.00-6 wt. % of a catalyst and 0.10-5 wt. % of a silica flow aid; (b) controlled release core/shell particles containing 10-70 wt. % of a hydrophobic active ingredient, 1.0-3.2 wt. % of an epoxidized oil, 21-64 wt. % of a polysaccharide, 7.6-23% of an amine-functionality containing material, and 0.10-5 wt. % of a silica flow aid; and (c) hybrid particles wherein the core/shell particles are contained in a matrix. Also disclosed are methods for making the particles and compositions containing the particles.

A composition suitable for treating a variety of medical, aesthetic and cosmetic conditions in mucous membranes and occluded skin areas, comprising hyaluronic acid, N-acetylcysteine, an active agent and set to pH of less than 6, which is characterized by high in vivo stability, is disclosed, as well as uses thereof in temporally extended delivery of active agent to mucous membrane in bodily sites.