The invention provides polyglycerol alkoxylate esters and for the preparation and use thereof.

The invention provides polyglycerol alkoxylate esters and for the preparation and use thereof.

The present invention discloses a matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid group.

The invention relates to a composition for reducing fatty tissue including at least one non-ionic surfactant as an active substance for reducing fatty tissue, wherein said non-ionic surfactant is polidocanol and the solvent is water, and a method for reducing unwanted fatty tissue by administering the composition.

The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein.

The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein.

ABSTRACT: A formulation of Collagen peptides with enzyme inhibitors and hyaluronic acid would increase the levels of collagen and elastin and hyaluronic acid for a long period of time, and would decrease the rate of aging, and age-related changes in the skin and other organs. During aging, the levels of these molecules decrease because of enhanced activities of their respective enzymes. Current approach has utilized collagen peptides alone to increase the levels of collagen and elastin in order to maintain healthy skin. In the absence of inhibitors of enzymes collagenase and elastase, and hyaluronic acid, the levels of collagen peptides, elastin, and hyaluronic acid would decrease. Consequently, the beneficial effects of collagen peptides alone would be reduced within a short period of time.

ABSTRACT: A formulation of Collagen peptides with enzyme inhibitors and hyaluronic acid would increase the levels of collagen and elastin and hyaluronic acid for a long period of time, and would decrease the rate of aging, and age-related changes in the skin and other organs. During aging, the levels of these molecules decrease because of enhanced activities of their respective enzymes. Current approach has utilized collagen peptides alone to increase the levels of collagen and elastin in order to maintain healthy skin. In the absence of inhibitors of enzymes collagenase and elastase, and hyaluronic acid, the levels of collagen peptides, elastin, and hyaluronic acid would decrease. Consequently, the beneficial effects of collagen peptides alone would be reduced within a short period of time.

A rheological solid personal care composition comprises a crystallizing agent, a suspension agent, an insoluble active, and an aqueous phase. A process for the manufacture of a rheological solid composition comprises the steps of: provision and heat up of an aqueous solution of sodium chloride, and sodium hydroxide; addition of an emulsifier, preferably palmitic acid, in order to obtain an emulsifier main mix, preferably a sodium palmitate soap main mix; addition of a suspension agent, preferably xanthan gum and glycerin, to the emulsifier main mix; addition of an insoluble active premix to the emulsifier main mix to obtain a blend, the insoluble active premix preferably being a petrolatum-based premix of topical drug actives, the topical drug active preferably selected from the group of: menthol, nutmeg, camphor, eucalyptus, cedar leaf, thymol, and any combinations thereof; cool down of the blend in order to form a crystalline structure of the rheological solid composition; optionally, addition of a hygroscopic stabilizer to the blend in order to stabilize the crystalline structure, the hygroscopic stabilizer preferably being sodium lactate.

A rheological solid personal care composition comprises a crystallizing agent, a suspension agent, an insoluble active, and an aqueous phase. A process for the manufacture of a rheological solid composition comprises the steps of: provision and heat up of an aqueous solution of sodium chloride, and sodium hydroxide; addition of an emulsifier, preferably palmitic acid, in order to obtain an emulsifier main mix, preferably a sodium palmitate soap main mix; addition of a suspension agent, preferably xanthan gum and glycerin, to the emulsifier main mix; addition of an insoluble active premix to the emulsifier main mix to obtain a blend, the insoluble active premix preferably being a petrolatum-based premix of topical drug actives, the topical drug active preferably selected from the group of: menthol, nutmeg, camphor, eucalyptus, cedar leaf, thymol, and any combinations thereof; cool down of the blend in order to form a crystalline structure of the rheological solid composition; optionally, addition of a hygroscopic stabilizer to the blend in order to stabilize the crystalline structure, the hygroscopic stabilizer preferably being sodium lactate.