The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Disclosed herein are organic-inorganic hybrid materials, in particular polyionic nanoclays, along with methods of making and using the same. The functionalized organic-inorganic hybrid materials are preferably of a phyllosilicate structure and comprise an octahedral ionic layer sandwiched between two tetrahedral layers, one or more charged chemical moieties covalently bonded to the tetrahedral layers, and optionally one or more counterions or functional groups associated with the hybrid materials. Methods of producing the same, by contacting a silane with a nucleophile and hydrolyzing the product thereof in the presence of a metal salt, are also provided.

Disclosed herein are organic-inorganic hybrid materials, in particular polyionic nanoclays, along with methods of making and using the same. The functionalized organic-inorganic hybrid materials are preferably of a phyllosilicate structure and comprise an octahedral ionic layer sandwiched between two tetrahedral layers, one or more charged chemical moieties covalently bonded to the tetrahedral layers, and optionally one or more counterions or functional groups associated with the hybrid materials. Methods of producing the same, by contacting a silane with a nucleophile and hydrolyzing the product thereof in the presence of a metal salt, are also provided.

Methods for removing one or more contaminants from an aqueous stream comprising: adding one or more hydraulic binders and one or more promoters to the aqueous stream, and separating the contaminants from the aqueous stream are provided. The methods may be used for removing contaminants that are arsenic-based, selenium-based, cadmium-based, zinc-based, mercury-based, iron-based, chromium-based and/or phosphate-based.

The invention relates to sulfonated aminomethylated chelate resins, to a method for producing same, to the use thereof for obtaining and purifying metals, in particular rare earth metals, from aqueous solutions and organic liquids, and for producing highly pure silicon.

The invention relates to sulfonated aminomethylated chelate resins, to a method for producing same, to the use thereof for obtaining and purifying metals, in particular rare earth metals, from aqueous solutions and organic liquids, and for producing highly pure silicon.

Described herein are passive samplers, making of such samplers, and methods of use. In an example embodiment, a passive sampling membrane comprises, for example, a continuous mesoporous sequestration media having a sequestration phase and a support membrane configured to support the sequestration phase. The sequestration phase may include a hydrophobic region and a hydrophilic region. The continuous mesoporous sequestration media may be configured to simultaneously sequester polar and non-polar organic substances.

Described herein are passive samplers, making of such samplers, and methods of use. In an example embodiment, a passive sampling membrane comprises, for example, a continuous mesoporous sequestration media having a sequestration phase and a support membrane configured to support the sequestration phase. The sequestration phase may include a hydrophobic region and a hydrophilic region. The continuous mesoporous sequestration media may be configured to simultaneously sequester polar and non-polar organic substances.

A production method for a liquid high purity sugar derivative-modified silicone or a composition thereof is disclosed. The method comprises the steps of: 1) capturing hydrophilic impurities in solid particles by causing an impurity containing composition containing liquid sugar derivative-modified silicone and the hydrophilic impurities derived from a sugar derivative to contact the solid particles, the sugar derivative being a hydrophilic modifier of the sugar derivative-modified silicone, and the solid particles being able to capture the hydrophilic impurities; and 2) separating the sugar derivative-modified silicone and the solid particles. The method is useful for production of the liquid high purity sugar derivative-modified silicone and the composition thereof on a commercial scale.

A production method for a liquid high purity sugar derivative-modified silicone or a composition thereof is disclosed. The method comprises the steps of: 1) capturing hydrophilic impurities in solid particles by causing an impurity containing composition containing liquid sugar derivative-modified silicone and the hydrophilic impurities derived from a sugar derivative to contact the solid particles, the sugar derivative being a hydrophilic modifier of the sugar derivative-modified silicone, and the solid particles being able to capture the hydrophilic impurities; and 2) separating the sugar derivative-modified silicone and the solid particles. The method is useful for production of the liquid high purity sugar derivative-modified silicone and the composition thereof on a commercial scale.