A filter comprising a casing and a plurality of filtering elements stacked between a first cover and a second cover, wherein the first cover rests against the casing in a stacking direction of the filtering elements, wherein the filter further comprises a cover backing coupled to the second cover by a return system configured to return the second cover towards the first cover, wherein the cover backing rests against the casing in the stacking direction and the second cover separates a zone of the casing adapted to receive filtered fluid from a zone of the casing adapted to receive fluid to filter.

A filter apparatus and method utilize a filter element having a central winding frame and a length of fluted filter material wound about the frame with the flutes of the media oriented substantially longitudinally, to thereby provide for filtration of a flow of fluid passing axially through the filter element. The winding frame is a substantially open, truss-like structure, having a smooth outer periphery and an axially extending winding feature to facilitate pulling the media into intimate contact with the smooth outer periphery during fabrication of the filter element. A leading edge of the filter media is anchored to a leading edge of the frame by a length of tape.

Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.

A filter may include: a first member having a first surface provided with a channel; and a second member set with a second surface thereof covering the channel. The first member may include a first passable portion that allows a fluid to pass between the first surface and a first space, which is defined beside a surface of the first member opposite to the first surface, through a first area of the channel. The second member may include a second passable portion that allows the fluid to pass between the second surface and a second space, which is defined beside a surface of the second member opposite to the second surface, through a second area of the channel distanced from the first area.

A filter apparatus and method utilize a filter element having a central winding frame and a length of fluted filter material wound about the frame with the flutes of the media oriented substantially longitudinally, to thereby provide for filtration of a flow of fluid passing axially through the filter element. The winding frame is a substantially open, truss-like structure, having a smooth outer periphery and an axially extending winding feature to facilitate pulling the media into intimate contact with the smooth outer periphery during fabrication of the filter element. A leading edge of the filter media is anchored to a leading edge of the frame by a length of tape.

A separation or reaction unit (1; 1; 81; 81; 101) and a method for aseptically connecting such units. The separation or reaction unit (1; 1; 81; 81; 101) comprises at last one fluid inlet (3a, 3b, 5a, 5b; 3a, 3b, 5a, 5b; 85a, 85b; 103a, 103b) and at least one fluid outlet (3a, 3b, 5a, 5b; 3a, 3b, 5a, 5b; 85a, 85b; 103a, 103b). At least one of the inlet or outlet is sealed by at least one film (7, 9; 11; 87a, 87b; 107a, 107b) and the contact surface between the film and the separation or reaction unit is aseptic. The films are adapted to be mated with a corresponding film on another separation or reaction unit or on a fluid distribution unit (20; 57; 61) which the separation or reaction unit possibly should be connected with and said mated films are adapted to be pulled out together two and two after mating such that corresponding fluid inlets/outlets on the two connected units are mated aseptically.

A method for removal of a foulant from a carrier gas is disclosed. A solids conveyance device that spans a vessel is provided, comprising an enclosed section and a filtering section. A cryogenic liquid and the carrier gas are provided to the enclosed section. The foulant condenses, dissolves, or desublimates into the cryogenic liquid, forming a cryogenic slurry and a foulant-depleted carrier gas entrained in the cryogenic slurry. The solids conveyance device advances the cryogenic slurry into the filtering section. The foulant-depleted carrier gas leaves the vessel through an upper portion of the permeable exterior wall and a warmed cryogenic liquid is removed from the cryogenic slurry through a lower portion of the permeable exterior wall, resulting in a solid foulant that is passed out of the solids outlet. In this manner, the foulant is removed from the carrier gas.

The present invention provides, among other things, methods for purifying mRNA based on normal flow filtration for therapeutic use.

The present invention provides, among other things, methods for purifying mRNA based on normal flow filtration for therapeutic use.

A method for the forced dewatering, by pressing, of saline residues produced by drinking water production, or by the treatment of municipal or industrial wastewaters, in which method the saline residues are introduced into the cylinder (12a) of a piston press (12) comprising flexible drains (12e) formed by flexible sheaths from a material that is permeable to liquid but impermeable to solids, each drain (12e) comprising an inner passage that opens into an associated opening (12g), the press operating in batches, and characterized in that during pressing, the piston carries out reciprocal movements and applies alternating and variable pressures to the sludge, while the flexible drains are deformed, the liquid pressed out from the product passing through the wall of the drains and being discharged as a filtrate, while the dewatered sludge remains outside the drains and is discharged by opening the press.