The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.

A method for manufacturing bubbles of the present invention includes: injecting an aqueous liquid 10 into a container 20 to a predetermined height; and vibrating the container at the number of revolution of equal to or high than 5,000 rpm such that the aqueous liquid 10 repeatedly collides with an inner surface of the container 20. According to the manufacturing, simply by vibrating the container 20 at a predetermined number of revolution, a large amount of bubbles 1 having a uniform size can be stably generated in the aqueous liquid 10. Furthermore, the vibrating the container 20 is preferably performed in a state where an internal pressure of the container 20 is higher than 1.0 atm.

A bubble manufacturing container 20 of the present invention includes: a container body 21 having an opening portion; and a rubber stopper 221 provided on the opening portion of the container body 21. The rubber stopper 221 is constituted so that the bubbles 1 of an inside of the container body 21 are able to be taken by piercing an injection needle. It is preferred that the bubble manufacturing container 20 has a fastening portion 222 provided on the rubber stopper 221, having an opening and sealing the container body 21 with the rubber stopper 221. Furthermore, it is preferred that the container body 21 mounts a weight portion.

A device for extracting polysaccharide from Acaudina molpadioides is provided, which includes a mixing box, a blocking cover, a feed pipe group, a discharge pipe, a bottom plate, a side plate, a first motor, a first transmission shaft, two drive shafts, a first circular gear, two second circular gears, two rotary discs, two connecting frame groups, two semiarc rotary discs, a slide bar, a stop collar, a fixed link, a baffle, a first bushing group and a first sleeve spring group. A top side wall and a rear lower side of the mixing box are communicated with the feed pipe group and the discharge pipe, respectively. Front side and rear sides of the slide bar are longitudinally connected with multiple first engaging teeth. Both the two semiarc rotary discs are connected with multiple second engaging teeth. The fixed link is connected between the stop collar and the slide bar.

A vertical motion mixer has a drive mechanism with two axes of guidance for vertical motion. A reciprocating yoke is fixedly secured to the driving shaft for the mixer, without any guide bearing for the mixer driving shaft. The mixer drive unit is of compact and simplified design with minimal moving parts, and including drive gearing with planetary gears to minimize wear during reciprocating movement.

A mixing machine configured to receive a receiving device in order to form a mixing machine, the manufacturing apparatus comprising: a support defining a receiving housing, having a first receiving location configured to receive a first deformable capsule and a second receiving location configured to receive a second deformable capsule, the first and second capsules fluidly linked and respectively containing a first formulation and a second formulation, an actuation system movable relative to the support inside the receiving housing, comprising a first actuation member positioned on one side of the receiving housing and movable thereinside, in order to transmit a pressure force on the first capsule, along a first actuation stroke, a second actuation member positioned on another side, preferably an opposite side, of the receiving housing and movable thereinside, in order to transmit a pressure force on the second capsule, along a second actuation stroke, in which the first actuation stroke has a different length from the second actuation stroke.

A method, for manufacturing bubbles of the present invention includes: mixing and aqueous liquid 10 with a gas 3; and applying vibration (an external force) to the aqueous liquid 10 and the gas 3 to generate a plurality of bubbles 1 constituted with the gas in the aqueous liquid 10. A diameter of the bubbles 1 to be generated in adjusted by changing a kind and/or an amount of an additive to be added to the aqueous liquid 10. In this way, it is possible to provide a method for manufacturing bubbles that makes it possible to wasily and reliably adjust the diameter of the bubbles to be generated. The additive to be added to the aqueous liquid 10 includes at least on kind of additive among a protein, salts, and sugars.

The disclosure relates to devices and methods for analyzing particles in a sample. In various embodiments, the present disclosure provides devices and methods for cytometry and additional analysis. In various embodiments, the present disclosure provides a cartridge device and a reader instrument device, wherein the reader instrument device receives, operates, and/or actuates the cartridge device. In various embodiments, the present disclosure provides a method of using a device as disclosed herein for analyzing particles in a sample.

A compounding platform including a compounding station having a user interface and a rotating device. The compounding platform including a chamber coupled to the compounding station. The rotating device is coupled to the chamber and configured to rotate the chamber relative to the compounding station. The compounding platform further including a consumable configured to be disposed within the chamber and including a plurality of ports and a bladder in fluid communication with the plurality of ports. The compounding platform has a first vial removably coupled to the consumable via a first port of the plurality of ports and including a diluent fluid, and a second vial removably coupled to the consumable via a second port of the plurality of ports and including a medicament. The compounding platform includes a plurality of valves configured to control fluid flow into and out of the bladder and corresponding to the plurality of ports.

A compounding platform including a compounding station having a user interface and a rotating device. The compounding platform including a chamber coupled to the compounding station. The rotating device is coupled to the chamber and configured to rotate the chamber relative to the compounding station. The compounding platform further including a consumable configured to be disposed within the chamber and including a plurality of ports and a bladder in fluid communication with the plurality of ports. The compounding platform has a first vial removably coupled to the consumable via a first port of the plurality of ports and including a diluent fluid, and a second vial removably coupled to the consumable via a second port of the plurality of ports and including a medicament. The compounding platform includes a plurality of valves configured to control fluid flow into and out of the bladder and corresponding to the plurality of ports.