In one example, a dispenser platform can include an enclosure that includes a first actuator to move a support in a first plane, wherein a portion of the support extends outside the enclosure, and a second actuator coupled to the portion of the support that extends outside the enclosure to move a stage coupled to the support in a second plane.

The present disclosure also relates to systems and methods for quality control in histology systems. In some embodiments, a method is provided that includes receiving a tissue block comprising a tissue sample embedded in an embedding material, imaging the tissue block to create a first imaging data of the tissue sample in a tissue section on the tissue block, removing the tissue section from the tissue block, the tissue section comprising a part of the tissue sample, imaging the tissue section to create a second imaging data of the tissue sample in the tissue section, and comparing the first imaging data to the second imaging data to confirm correspondence in the tissue sample in the first imaging data and the second imaging data based on one or more quality control parameters.

An incubation cassette for reducing liquid evaporation from wells of a microplate with a frame for receiving a microplate with wells, the frame having a central first opening surrounded by an inner wall, the dimensions are designed for inserting a microplate, and the frame having an outer wall that runs essentially parallel to the inner wall and which is attached to the inner wall connects so that a liquid reservoir surrounding the first central opening for receiving a liquid is formed by the two walls and the intermediate base is disclosed. The incubation cassette also includes a float provided in the liquid reservoir that can be brought into fluid contact with the liquid held in the liquid reservoir in such a way that the float is in relation to the liquid level of the liquid in the liquid reservoir absorbed liquid experiences buoyancy.

Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Disclosed in one aspect is a method for performing a complete blood count (CBC) on a sample of whole blood by metering a predetermined amount of the whole blood and mixing it with a predetermined amount of diluent and stain and transferring a portion thereof to an imaging chamber of fixed dimensions and utilizing an automated microscope with digital camera and cell counting and recognition software to count every white blood cell and red blood corpuscle and platelet in the sample diluent/stain mixture to determine the number of red cells, white cells, and platelets per unit volume, and analyzing the white cells with cell recognition software to classify them.

The present disclosure provides devices, machines and methods for incubating or washing a biological sample membrane or gel automated processing of biological samples. This disclosure provides a device comprising a washing cassette, a sample holder, a poking gear and a washing basin assembly. The disclosure also provides machines comprising the device and methods using the device.

The invention concerns a frame (1) for holding a plurality of filtration assemblies (100) and a testing unit (10) for microbiological testing. The frame (1) for holding the plurality of filtration assemblies (100) comprises an array of supports (5) each configured to receive and support one of the filtration assemblies (100) on a common support plane (2), and connection means (6) provided on the periphery (7) of the frame (1) and configured to releasably connect, by a form-locking engagement, a further frame (1) such that the common support planes (2) of the connected frames (1) are contiguous. Further, the testing unit (10) comprises at least one frame (1) packed in a bag (20) in pre-sterilized condition.

The present invention relates to an apparatus for performing a nucleic acid amplification reaction and a fluorescence detection device for reaction analysis. The nucleic acid amplification apparatus of the present invention uses a plurality of blocks having different reaction temperatures by independent temperature control and the movement between the blocks is performed along sliding recesses formed in the blocks, enabling to greatly shorten the total amplification time (TAT). In the fluorescence detection device of the present invention, the positions of the light source and the photodetector are very unique for the reaction vessel in which an excitation light is provided and an emission light is generated.

The present invention is directed to an apparatus and method of fabricating a sealed storage system for environmentally sensitive aqueous materials with liquid flow control and on-demand distribution. The present invention features a sealed storage apparatus capable of compactly containing a liquid reagent with liquid control capabilities. The apparatus may comprise a liquid-impermeable, air-impermeable, resistant to force-induced tearing pouch body capable of being penetrated through the application of a laser. The apparatus may further comprise a pouch cavity disposed within the pouch body for holding the liquid reagent. The apparatus may further comprise a liquid-impermeable, air-impermeable, and resistant to force-induced tearing sealing adhesive disposed over the pouch cavity to seal the liquid reagent within the pouch body capable of being penetrated through the application of the laser. Thus, the apparatus may allow liquid to flow from any point on the said apparatus by simply directing the laser to the point.

The present invention is directed to an apparatus and method of fabricating a sealed storage system for environmentally sensitive aqueous materials with liquid flow control and on-demand distribution. The present invention features a sealed storage apparatus capable of compactly containing a liquid reagent with liquid control capabilities. The apparatus may comprise a liquid-impermeable, air-impermeable, resistant to force-induced tearing pouch body capable of being penetrated through the application of a laser. The apparatus may further comprise a pouch cavity disposed within the pouch body for holding the liquid reagent. The apparatus may further comprise a liquid-impermeable, air-impermeable, and resistant to force-induced tearing sealing adhesive disposed over the pouch cavity to seal the liquid reagent within the pouch body capable of being penetrated through the application of the laser. Thus, the apparatus may allow liquid to flow from any point on the said apparatus by simply directing the laser to the point.