A rotor core is provided that includes a rotor length defined along an axis of rotation and a plurality of separation channels. The plurality of separation channels having a channel length extending along the axis of rotation a distance that is less than the rotor length. A rotor assembly is also provided that includes such a rotor core removably disposed in an outer housing.

A compact and portable multi-stage centrifuge apparatus comprising a cart, a housing mounted onto the cart, and an engine mounted onto the cart adjacent to the housing, wherein the housing comprises an inlet in the top of the housing, an outlet in the wall of the housing, and a bowl contained within the housing, wherein the bowl comprises an engagement member that is operatively coupled to the engine's drive shaft, such that the bowl can be rotated by engaging the engine, thus removing undesirable materials from the bowl and out of the housing through the outlet.

An enhanced gravity separation device rotates a plurality of rectangular section vessels about a central drive shaft. Each vessel has an array of closely spaced plates positioned with the vessel between outer regions and inner regions. A feed of mixed dense and less dense fluid matter is fed to the outer regions via a pipe and conduits, through the plate arrays and into the inner regions. Overflow of less dense matter reports to the inner regions and underflow of denser matter reports to the outer region. The vessels may be fluidized by liquid supplied into the outer regions via annulus and conduits.

An enhanced gravity separation device rotates a plurality of rectangular section vessels about a central drive shaft. Each vessel has an array of closely spaced plates positioned with the vessel between outer regions and inner regions. A feed of mixed dense and less dense fluid matter is fed to the outer regions via a pipe and conduits, through the plate arrays and into the inner regions. Overflow of less dense matter reports to the inner regions and underflow of denser matter reports to the outer region. The vessels may be fluidized by liquid supplied into the outer regions via annulus and conduits.

Cell separation systems and methods of separating cells are disclosed. In an embodiment, a cell separation system is described that comprises a non-transitory storage device that executes a centrifugation program to separate cell volume from biologic material volume; a heating mechanism; a containment mechanism; and an assembly comprised of a single-walled centrifugation bowl. In an embodiment, methods of separating cells are disclosed whereby cells are separated by agitating a volume of biologic material and a volume digestion media to form a digested volume of biologic material; centrifuging the digested volume of biologic material; removing a portion of a resulting waste via at least one fluid outlet; isolating a different portion of the waste, and removing the concentrated cell volumes from the reservoir.

Cell separation systems and methods of separating cells are disclosed. In an embodiment, a cell separation system is described that comprises a non-transitory storage device that executes a centrifugation program to separate cell volume from biologic material volume; a heating mechanism; a containment mechanism; and an assembly comprised of a single-walled centrifugation bowl. In an embodiment, methods of separating cells are disclosed whereby cells are separated by agitating a volume of biologic material and a volume digestion media to form a digested volume of biologic material; centrifuging the digested volume of biologic material; removing a portion of a resulting waste via at least one fluid outlet; isolating a different portion of the waste, and removing the concentrated cell volumes from the reservoir.

Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation.

An apparatus for facilitating particle separation by density includes a separator having an inner surface surrounding a rotation axis and defining a particle path from an input end to an axially spaced output end. The inner surface includes a plurality of axially spaced dividers having respective inner positions, defining at least in part respective axially spaced retainers for collecting particles during rotation of the separator. The retainers each include at least one fluid inlet for fluidizing particles in the retainer during operation. The dividers include a first pair of adjacent dividers and a second pair of adjacent dividers, the first pair nearer the input end than the second pair, wherein a first divider slope of the first pair is greater than a second divider slope of the second pair and wherein each of the first and second divider slopes is zero or positive. Other systems, apparatuses and methods are disclosed.

A liner for a filter sub-assembly has a wall having an innermost surface that bounds a cavity extending between opposing first and second ends of the liner. The wall has a deflected portion extending into the cavity and delimiting an opening. The liner may be used in a rotor of a filter assembly.

A liner for a filter sub-assembly has a wall having an innermost surface that bounds a cavity extending between opposing first and second ends of the liner. The wall has a deflected portion extending into the cavity and delimiting an opening. The liner may be used in a rotor of a filter assembly.