A centrifuge system including a centrifuge housing having a cavity at least partially surrounded by an outer shell, a central shaft extending into at least a portion of the cavity, a rotary motion source for rotating the centrifuge housing, and a filter concentrically positioned about the central shaft. The filter includes a first layer adjacent to a second layer, wherein the first and second layers are wound into a roll about a central longitudinal opening. The first layer may include at least one contaminant retention layer and the second layer may include at least one flow defining layer.

A centrifuge system including a centrifuge housing having a cavity at least partially surrounded by an outer shell, a central shaft extending into at least a portion of the cavity, a rotary motion source for rotating the centrifuge housing, and a filter concentrically positioned about the central shaft. The filter includes a first layer adjacent to a second layer, wherein the first and second layers are wound into a roll about a central longitudinal opening. The first layer may include at least one contaminant retention layer and the second layer may include at least one flow defining layer.

A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.

Provided herein are devices and methods for the capture or isolation of a biomarker from a biological sample. In several embodiments, the device comprises a loading region, a filter material, and a receiving region. In particular, in several embodiments, biological fluid is passed from the loading region through the filter material and into the receiving region, thereby resulting in capture or isolation of a biomarker.

Provided herein are devices and methods for the capture or isolation of a biomarker from a biological sample. In several embodiments, the device comprises a loading region, a filter material, and a receiving region. In particular, in several embodiments, biological fluid is passed from the loading region through the filter material and into the receiving region, thereby resulting in capture or isolation of a biomarker.

A discontinuously operated centrifuge, in particular sugar or starch centrifuge, includes a rotating, cylindrical centrifuge basket having a casing provided with openings and having an upper open end. An inner screen element formed as a composite unit of a screen mat and a support mat is insertable as a prefabricated, single-piece screen element into the centrifuge basket via the upper open end thereof. The screen element has ends abutting in a circumferential direction within the centrifuge basket, with axially extending end strips attached to the abutting ends of the screen element. A closure element in the form of an axially extending clamping strip cooperates with the end strips so as to lock and radially brace the screen element against the centrifuge basket casing. Attached on the centrifuge basket is an upper limiting flange, with an annular cover being screwed onto an upper limiting flange for securing the screen element.

A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.

A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.

Disclosed is a device structure for multistage water-air separation of a cleaning machine, where an inner wall of a water-air separation box, an outer wall and a bottom plate of a structure part, and a coarse filter screen are enclosed into a primary separation bin, the primary separation bin surrounds the structure part as a center, a side wall of the water-air separation box is provided with an air inlet duct, one end of the air inlet duct is provided with an air outlet and extends into the primary separation bin, the air outlet of the air inlet duct faces a circumferential direction of the primary separation bin, the side wall of the water-air separation box is also provided with a water outlet communicated with an interior of the primary separation bin, and a first opening is connected with a main motor having a suction function.

Disclosed is a device structure for multistage water-air separation of a cleaning machine, where an inner wall of a water-air separation box, an outer wall and a bottom plate of a structure part, and a coarse filter screen are enclosed into a primary separation bin, the primary separation bin surrounds the structure part as a center, a side wall of the water-air separation box is provided with an air inlet duct, one end of the air inlet duct is provided with an air outlet and extends into the primary separation bin, the air outlet of the air inlet duct faces a circumferential direction of the primary separation bin, the side wall of the water-air separation box is also provided with a water outlet communicated with an interior of the primary separation bin, and a first opening is connected with a main motor having a suction function.