The invention relates to a method for producing a prosthesis or partial prosthesis based on digital data, using multiple teeth present in a dental arch (14) and a prosthesis base to be produced, characterized in that the prosthesis base is rough-milled by means of a milling tool, i.e. is milled in a first step, and in that the prosthesis base present as a semi-finished product, in particular in regions of the prosthesis base on which the teeth and the prosthesis base abut against each another and/or are to be bonded to each other, is partially milled, i.e. is milled in a second step, by means of an in particular different milling tool, thereby being brought to a target height which corresponds to the desired bonding gap between the prosthesis base and the tooth or dental arch (14).

Various embodiments of manufacturing pistol frames are described. According to various embodiments, a left pistol frame portion is fabricated. A separate right pistol frame portion is also fabricated. The left pistol frame portion is attached to the right pistol frame portion to form a pistol frame.

A method of forming a microneedle array can include forming a sheet of material having a plurality of layers and micromilling the sheet of material to form a microneedle array. At least one of the plurality of layers can include a bioactive component, and the microneedle array can include a base portion and plurality of microneedles extending from the base portion.

A method of forming a microneedle array can include forming a sheet of material having a plurality of layers and micromilling the sheet of material to form a microneedle array. At least one of the plurality of layers can include a bioactive component, and the microneedle array can include a base portion and plurality of microneedles extending from the base portion.

A method of forming a microneedle array can include forming a sheet of material having a plurality of layers and micromilling the sheet of material to form a microneedle array. At least one of the plurality of layers can include a bioactive component, and the microneedle array can include a base portion and plurality of microneedles extending from the base portion.