A method for preparing keratin-based composites includes mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and solvent casting the nanoparticle-keratin solution to form the keratin-based composites.

A bonded multilayer article including: (a) at least one first layer of a silicone-containing rubber substrate material bonded to (b) at least one second layer of a substrate material bondable to the first layer; wherein at least a portion of the surface of the first layer is activated for adhesion to increase the bond strength of the first layer to a second layer such that the bond strength of the first layer bonded to the second layer is increased; and a process for producing the above bonded multilayer article.

A cryo formulation-based microneedle device for transdermal delivery of bioactive therapeutic agents. The microneedle device includes: one or more microneedle patches each including an array of miniaturized needles, wherein each miniaturized needle defining a base end and a tip; and a substrate to which the base end of the array of miniaturized needles is attached or integrated thereto; wherein the microneedle patch is in a cryo status; wherein each of the one or more microneedle patch is adapted to be applied on a skin surface, in which the miniaturized needles penetrates into skin; and wherein the miniaturized needles is further arranged to melt so as to release one or more bioactive therapeutic agents into the skin to achieve a targeted therapeutic effect.

A two-part formulation for a potting composition is provided that includes a part A including silicone polymer precursors, boron nitride present in an amount of from 20 to 60 total weight percent as particulate or 1 to 8 total weight percent as boron nitride nanotubes, a platinum or rhenium addition catalyst. A part B includes a hydride functional siloxane operative to cure the silicone polymer precursors and devoid of said platinum or rhenium addition catalyst. When cured in the presence of the voltage producing substrate, a potting is formed that has high thermal conductivity and low electrical conductivity.

According to one embodiment, a mixture includes a fluoropolymer monomer having at least one functional group amenable to polymerization, a pore-forming material, and a polymerization initiator. According to another embodiment, a product includes a porous three-dimensional structure comprising a crosslinked fluoropolymer, where at least 20% of a volume measured within an outer periphery of the porous three-dimensional structure corresponds to the pores.

A polishing pad for chemical mechanical polishing comprises a polishing layer which comprises a polymer matrix which is the reaction product of an isocyanate terminated oligomer or polymer, with a curative blend comprising two or more polyamine curatives wherein pores are present in the polymer matrix, such pores being formed by expansion of pre-expanded fluid filled polymeric microspheres such expansion occurring during reaction of the isocyanate terminated oligomer or polymer with the two or more curatives, wherein the polishing layer is characterized by one or more of a ratio of viscous modulus (G″) at 104° C. to shear loss modulus (G″) at 150° C. of at least 5:1; and a specific gravity of the polishing layer is less than or equal to 95% of a calculated specific gravity for the isocyanate terminated oligomer or polymer, the curative blend and the pre-expanded fluid filled polymeric microspheres.

Transparent articles and methods of producing transparent articles are provided. The transparent article includes hydrophobic nanoparticles dispersed within poly(methyl methacrylate). The method of producing transparent articles includes pouring a transparent article precursor into a mold, the transparent article precursor comprising nanoparticles, a solvent, and a polymer, and the mold comprising a flat surface. The method also includes placing the mold into a container having an adjustable opening and allowing the solvent to evaporate from the transparent article precursor, thereby forming the transparent article over the flat surface of the mold. The method further includes flattening the transparent article, in which flattening the transparent article includes positioning a flat article on a first side of the transparent article, and compressing the transparent article between the flat surface and the flat article.

A wound dressing includes a dressing member or body which has a wound-facing side intended to be placed adjacent a wound, such a surgical wound. The wound-facing side of the wound dressing is provided with a plurality of microstructures in the form of denticles. Each of the denticles includes a body that extends from a base of the denticle laterally over, but not connected to, the dressing member. The denticles are arranged in an overlapping manner such that the body of one denticle overlaps the body of one or two other adjacent denticles. The denticles create a microstructured surface that resists bioadhesion, and which, upon flex of the wound dressing, create mechanical interference with each other that can dislodge organisms that manage to adhere to the wound-facing side of the wound dressing in spite of the microstructured surface.

The manufacturing method comprises at least one processing step for a carbon-carbon composite part (100, 200). In a first variant, the method comprises steps for machining and a step for processing the part. In a second variant, the method comprises a crushing step for the part before the processing step and a moulding step after the processing step. Application to manufacturing timepiece components (170, 270).

The present disclosure provides processes for producing polyethylene resins. In at least one embodiment, a polyethylene has: a density of from about 0.91 g/cm.sup.3 to about 0.94 g/cm.sup.3; a value of Mz of about 1,500,000 g/mol or greater; and a ratio of Mz to Mw of about 7 or greater. A process includes introducing a first feed stream having ethylene monomer and a first free radical initiator to a first inlet of a first reaction zone, where the first reaction zone has a first inlet temperature. The process further includes introducing a second feed stream having ethylene monomer and a second free radical initiator to a second inlet of a second reaction zone, where the second reaction zone has a second inlet temperature that is the same or different than the first inlet temperature.