The present disclosure relates to a solid hair cosmetic composition comprisingbased on the total weight of the cosmetic compositionabout 30.0 to about 60.0% by weight of at least one polyhydric alcohol, and optionally: about 0.1 to about 15.0% by weight of at least one cationic surfactant, about 0.1 to about 20.0% by weight of at least one saturated or unsaturated, branched or unbranched C.sub.8-C.sub.30 alcohol and/or a saturated or unsaturated, branched or unbranched C.sub.8-C.sub.30 carboxylic acid and/or a salt of a saturated or unsaturated, branched or unbranched C.sub.8-C.sub.30 carboxylic acid, and about 0.1 to about 40.0% by weight of at least one polysaccharide, as well as production and application methods and uses thereof.

An injection molding apparatus and method of fabricating a molded part are provided. The apparatus may include a barrel, a nozzle enclosing an end of the barrel and defining an opening in fluid communication with an inside of the barrel, and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel. The extrusion screw may include a screw tip. Relative axial movement between the barrel and the extrusion screw may open or close the opening of the nozzle to permit or prevent, respectively, material flow through the opening of the nozzle. The method may include clamping a mold, opening a nozzle, rotating the extrusion screw to pump a molten material into the mold until the mold is filled, closing the nozzle, and unclamping the mold to release a molded part.

Provided is a method for manufacturing a microneedle array in which the distal end of a needle-like recessed portion is reliably filled with a drug solution. The problem is solved by a method for manufacturing a microneedle array, including: a positioning adjustment step of adjusting positioning of a mold having a needle-like recessed portion on a front surface, and a drug solution ejection nozzle which ejects a drug solution; a relative movement step of moving the mold and the drug solution ejection nozzle relative to each other to cause a position of the needle-like recessed portion and a position of the drug solution ejection nozzle to coincide with each other in a plan view in a direction parallel to an ejection direction of the drug solution; an ejection step of ejecting the drug solution from the drug solution ejection nozzle toward the needle-like recessed portion; and a suction step of suctioning a rear surface of the mold.

The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

A method of manufacturing a biocompatible polymer-based microneedle, the method comprising: (a) a primary filling step of covering, by stoppers, upper sides of multiple holes, which are formed to be spaced apart from one another, penetrate a mold, and each have a conical shape, and injecting a biocompatible polymer solution containing an appropriate amount of active ingredient by using filling needles; (b) a secondary filling step of injecting a biocompatible polymer solution containing an excipient by using the filling needles; (c) a step of solidifying the biocompatible polymer solution; and (d) a step of attaching a pad to an upper portion of the mold and then detaching the pad from the mold. The microneedle manufactured by the present invention may solve problems of degeneration of medicine, insufficient hardness, and a loss of medicine caused by a complicated process and a long manufacturing time.

A fabrication method for a water-absorbent filter includes obtaining a homogenized tragacanth suspension by dissolving tragacanth in a solvent, where the solvent may include distilled water, ethyl acetate, acetic acid, and formic acid, obtaining a support layer by coating a stainless steel mesh with a thin layer of a hydrophobic polymer, coating a stainless steel mesh with the thin layer of the hydrophobic polymer comprising electrospinning a hydrophobic polymer solution onto the stainless steel mesh, forming a tragacanth nanofibrous web on the support layer by electrospinning the homogenized tragacanth suspension onto the support layer, and cross-linking the tragacanth nanofibrous web by exposing the tragacanth nanofibrous web to a saturated vapor of a cross-linking agent.

A fabrication method for a filter containing tragacanthin-polyvinyl alcohol (PVA) nanofibers includes obtaining a homogenous tragacanthin-PVA solution by obtaining a PVA solution by dissolving PVA in distilled water, and adding tragacanthin to the PVA solution. The method may further include obtaining a support layer by coating a stainless steel mesh with a thin layer of a hydrophobic polymer, coating a stainless steel mesh with the thin layer of the hydrophobic polymer comprising electrospinning a hydrophobic polymer solution onto the stainless steel mesh, and forming a tragacanthin-PVA nanofibrous web on the support layer by electrospinning the homogenous tragacanthin-PVA solution onto the support layer.

The present invention relates to the use of a composition comprising isosorbide diglycidyl ether and a curing agent as a sacrificial support, to a sacrificial support comprising isosorbide repeating units, to methods for producing the sacrificial support of the invention and to uses of the sacrificial support of the invention for producing three-dimensional objects.

Embodiments of the disclosed technology generally include systems and methods for the replication of a vulva. This disclosed method and system provides an option for the creation of an adult pleasure device by replication of the consumer's vulva for use by his, her, or their partner for sexual pleasure in the absence of his, her, or their partner. However, the potential applications of this invention are not limited to such use, and have many uses, such as for a keepsake, an intimate gift, or a fun experience.

Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.