The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

A cardiac patch for treatment of a mammalian heart including perfusable vessels embedded integratedly between two layers of anisotropically oriented myocardial fibers. The cardiac patch is made using a dual 3D bioprinting technique using stereolithography to form an anisotropic construct and extrusion printing to form perfusion vessels. A nutrient and oxygen containing media can be provided within the perfusion vessels for growth of cells in the cardiac patch. The technique permits larger patches to be made for the treatment of cardiac damage in both small and large mammalian hearts.

A method for preparing keratin-based composites includes mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and solvent casting the nanoparticle-keratin solution to form the keratin-based composites.

The present invention provides methods for producing a silk protein spinning dope solution suitable for producing high toughness fibres, the thus produced silk protein spinning dope solution, methods for producing fibres using said silk protein spinning dope solution.

Methods and devices are described for using a controlled extensional strain to organize prefibrillar collagen and/or elastin solutions into an organized array of fibrils. The organized array of collagen fibrils produced by the disclosed methods and devices can be used for tissue engineering applications.

An artificial corneal stroma comprises a hydrogel substrate supported by artificial stents. At least one surface comprises a plurality of nanosize structures. The hydrogel substrate is formed from an artificial corneal stroma material. The artificial corneal stroma material comprises a methacrylate-bonded hyaluronic acid, a collagen, and a photoinitiator.

Provided is a molded article of a composition comprising a polypeptide, wherein the polypeptide is at least one kind selected from the group consisting of natural spider silk protein and polypeptides derived from natural spider silk protein.

The present invention provides, in one aspect, a method for producing a molded article, the method comprising exposing a molded article precursor comprising a protein to an environment with a relative humidity of 90% or more to obtain the molded article.

The invention relates to a biodegradable material made of biological components, comprising 10 to 60 wt. % of a protein adhesive (1), which is made of at least one protein, and 2 to 50 wt. % of natural fibers (4). Furthermore, 2 to 15 wt. % of at least one hygroscopic mineral (7), 10 to 55 wt. % of water (2), and 0 to 50 wt. % of an additive component (5) are provided in the material (10).

Ribulose-1,5-bisphosphate oxygenase (RuBisCO) protein films and a method of producing RuBisCO films are disclosed herein. A method of producing one or more RuBisCO protein films includes obtaining RubBisCO, for example from tobacco, combining the RuBisCO with one or more solvents, where the one or more solvents may be about 10% w/v the RuBisCO, mixing the RuBisCO and the one or more solvents to form a slurry, heating the slurry to about 70 degrees C., cooling the slurry to at least about 45 degrees C., dispensing the slurry into one or more molds for film formation, drying the slurry in the one more molds, and removing the one or more RuBisCO protein films formed within the one or more molds.