Provided is an antimicrobial composition comprised of at least one degradation product of oxidized cellulose (OC), such as oxidized regenerate cellulose (ORC), and minocycline, methods of preparation thereof and uses thereof.

Nutritional formulas comprising long-chain polyunsaturated fatty acids (LC-PUFAs) are provided, along with methods and devices for preparing and/or administering nutritional formulas. In some embodiments, a percentage of the LC-PUFAs in the nutritional formula are in the form of monoglycerides and/or free fatty acids. In some embodiments, the nutritional formulas do not comprise added lipase. Also provided are methods for providing nutrition to a subject, methods for improving fat absorption, methods for improving cognitive ability, methods for preventing chronic lung disease, and methods for reducing the length of time a patient requires total parenteral nutrition.

The invention relates to 5-({6-amino-2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-methylhexanoyl}amino)pyrazolo[1,5-a]pyridine-3-carboxamide, to processes for its preparation, to its use for the treatment and/or prophylaxis of diseases and to its use for the preparation of medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and edemas, and also ophthalmic disorders, and its use to inhibit disturbing plasma kallikrein activity for the conduct of extracorporeal procedures and analytical assays.

The invention relates to 5-({6-amino-2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-methylhexanoyl}amino)pyrazolo[1,5-a]pyridine-3-carboxamide, to processes for its preparation, to its use for the treatment and/or prophylaxis of diseases and to its use for the preparation of medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and edemas, and also ophthalmic disorders, and its use to inhibit disturbing plasma kallikrein activity for the conduct of extracorporeal procedures and analytical assays.

A method for predicting a likelihood of infection in a set of similarly sourced plant products is disclosed. A subset of plant products is selected from the set of plant products. For each plant product in the subset, a level of expression of one or more infection biomarkers, and optionally a level of expression of one more housekeeping biomarkers, are determined. A set of biomarker expression statistics for the subset of plant products is determined based on the determined levels of expression of the one or more infection biomarkers and optionally the levels of expression of the one or more housekeeping biomarkers for each plant product in the subset. A likelihood of infection in the set of plant products is then predicted based at least in part on the determined set of biomarker expression statistics for the subset of plant products.

The invention, in various embodiments, provides systems, methods and solutions for perfusing an organ.

A system for growing cells comprising a bioreactor chamber for growing the cells, a delivery system delivering a perfusion solution to the bioreactor chamber for perfusion of the perfusion solution through the cells, a dialysis system having a dialyzer, a dialysate for performing a dialysis and a filter for reducing ammonia content in said dialysate, and a controller that circulates the perfusion solution through the dialyzer and the dialysate through the filter.

An embalming machine for mixing of fluids and cleaning of a reservoir may include a reservoir. The embalming machine may include a tube extending from a lower portion to an upper portion of the reservoir, the tube providing a pathway for fluid to travel to the reservoir. The embalming machine may include a port connected to an end of the tube adjacent to the upper portion of the reservoir, the port being configured to dispense the fluid traveling through the tube and into an interior of the reservoir.

An embalming machine for mixing of fluids and cleaning of a reservoir may include a reservoir. The embalming machine may include a reservoir lid configured to at least partially enclose an upper portion of the reservoir, the reservoir lid including an access hatch integrated into the reservoir lid. The embalming machine may include an access hatch lid integrated into the reservoir lid, the access hatch lid being shaped to overlie the access hatch.

A method for blood serum protein activity preservation is provided. The method comprises the steps of mixing blood serum with one or more protectants selected from the group consisting of albumin, triglyceride, glycerol, dextran, propylene glycol, galactose, alginate, and trehalose; and lyophilizing the mixture.