A wash solution for remediating lubricant contamination in cytological specimens includes a Tris-based alkaline buffer solution. The buffer solution may be prepared in methanol, and may include a proton-rich protein, or a basic amino acid, such as arginine, lysine, or guanidine. A method for remediating a specimen contaminated with lubricant includes using the wash solution and/or adding a salt to the final vial prior to preparing the microscope slide. The method may include adding the wash solution to the specimen, centrifuging the specimen and wash solution to form a supernatant and cell pellet, decanting the supernatant, and adding a preservative solution to the cell pellet. The method may further include adding salt to a vial containing the preservative solution and cell pellet.

A wash solution for remediating lubricant contamination in cytological specimens includes a Tris-based alkaline buffer solution. The buffer solution may be prepared in methanol, and may include a proton-rich protein, or a basic amino acid, such as arginine, lysine, or guanidine. A method for remediating a specimen contaminated with lubricant includes using the wash solution and/or adding a salt to the final vial prior to preparing the microscope slide. The method may include adding the wash solution to the specimen, centrifuging the specimen and wash solution to form a supernatant and cell pellet, decanting the supernatant, and adding a preservative solution to the cell pellet. The method may further include adding salt to a vial containing the preservative solution and cell pellet.

A cell for treating neurodegenerative disease treated with angelica extract is provided. The pharmaceutical composition comprises the cell for treating neurodegenerative disease and can significantly increase and recover the number of dopaminergic neurons to achieve the goal for treating neurodegenerative disease.

Described are systems, methods, and devices relating to normothermic extracorporeal support of an organ, tissue, or bioengineered graft comprising cross-circulation (XC) perfusion for prolonged periods (days to weeks) via an XC perfusion circuit in connection with an extracorporeal host (e.g., animal, patient, organ transplant recipient) are disclosed. The XC perfusion circuit comprises auto-regulation of blood flow based on the trans-organ blood pressure difference between arterial and venous pressure. Recipient support enabled 36 h of normothermic perfusion that maintained healthy lungs with no significant changes in physiologic parameters and allowed for the recovery of injured lungs. Extended support enabled multiscale therapeutic interventions in all extracorporeal lungs. Lungs exceeded transplantation criteria.

A device and method for preserving organisms (e.g. causative organisms in a case of osteomyelitis) in a biopsy sample during transport or storage in a manner which obviates or mitigates deleterious effects of lengthy periods of transport or storage on the success rate of determining the identity of the organism and subsequent testing. The device includes a reservoir which contains a transport medium, an outlet for releasable connection with a biopsy sample housing (e.g. a syringe with a luer connector element) containing a biopsy sample, and a closure member to seal the outlet before use. The transport medium can be delivered from the reservoir to the syringe, when the two are connected, and the reservoir-syringe unit can be transported as a sealed unit.

A device and method for preserving organisms (e.g. causative organisms in a case of osteomyelitis) in a biopsy sample during transport or storage in a manner which obviates or mitigates deleterious effects of lengthy periods of transport or storage on the success rate of determining the identity of the organism and subsequent testing. The device includes a reservoir which contains a transport medium, an outlet for releasable connection with a biopsy sample housing (e.g. a syringe with a luer connector element) containing a biopsy sample, and a closure member to seal the outlet before use. The transport medium can be delivered from the reservoir to the syringe, when the two are connected, and the reservoir-syringe unit can be transported as a sealed unit.

The invention provides method for preparing amnion tissue grafts, as well as the grafts themselves. In specific embodiments, the tissue graft comprises a single layer of dried amnion from an umbilical cord.

Provided is a device for vitrification-based cryopreservation which enables easy and reliable vitrification freezing of cells or tissues. The device of the present invention for cell or tissue cryopreservation by vitrification has a porous structure made of a material having a refractive index of 1.45 or less as a vitrification solution absorber.

In one embodiment, a freezer system has one or more shelves, each shelf has shelf electronics and can receive one or more racks, each rack has rack electronics and one or more cells for receiving one or more boxes of samples, each box has one or more RFID tags. Freezer electronics communicate with the outside world and with each set of shelf electronics. Each set of rack electronics communicates wirelessly with the corresponding set of shelf electronics and with the corresponding box RFID tags. Power for the rack electronics is derived from wireless signals from the shelf electronics. The freezer system can detect the presence of racks on shelves and boxes on racks to track the location and the orientation of each received box.

In one embodiment, a freezer system has one or more shelves, each shelf has shelf electronics and can receive one or more racks, each rack has rack electronics and one or more cells for receiving one or more boxes of samples, each box has one or more RFID tags. Freezer electronics communicate with the outside world and with each set of shelf electronics. Each set of rack electronics communicates wirelessly with the corresponding set of shelf electronics and with the corresponding box RFID tags. Power for the rack electronics is derived from wireless signals from the shelf electronics. The freezer system can detect the presence of racks on shelves and boxes on racks to track the location and the orientation of each received box.