A01N1/00

A CHEMICAL COMPOSITION TO STABILIZE EXTRACELLULAR VESICLES IN A BLOOD SAMPLE AND METHOD OF USE THEREOF
20190254273 · 2019-08-22 · ·

Stabilizing compositions for stabilizing a post-phlebotomy, but pre-analysis, blood samples include a metabolic inhibitor, a protease inhibitor, a buffer system, an anticoagulant, and a solvent. The stabilizing compositions stabilize a post-phlebotomy blood sample to preserve the physiological state of the blood sample for later analysis. The analysis performed on the stabilized blood sample may determine the state of an analyte in a blood sample for diagnosis. The stabilizing compositions may stabilize the post-phlebotomy blood sample for at least 6 hours, and up to 672 hours. More preferably, the stabilizing composition has an undetectable level of formaldehyde before contact with the post-phlebotomy blood sample, so that cross linking of proteins and cross linking of proteins to nucleic acids in the post-phlebotomy blood sample is minimized. The stabilizing composition has a test sensitivity rate of 1 for up to 672 hours.

APPARATUS AND METHOD FOR PRESERVING MUCOSA

A mixing apparatus (1) for mixing slaughter offal with a preservative agent, the apparatus comprising an offal collection tank (3) with a bottom (4) provided with a discharge opening (5) connectable to a closable discharge, an agitator (8) extending into the offal collection tank, and a pump unit (9) operatively connectable to the discharge, wherein the apparatus further comprises a preservative reservoir (7) mounted on top of the collection tank (3). A collection and preservation system is provided, wherein the addition of preservation agent can be strictly controlled, can easily and quickly be installed and connected when it is to be used. After use, the system is easily removed and cleaned.

APPARATUS AND METHOD FOR PRESERVING MUCOSA

A mixing apparatus (1) for mixing slaughter offal with a preservative agent, the apparatus comprising an offal collection tank (3) with a bottom (4) provided with a discharge opening (5) connectable to a closable discharge, an agitator (8) extending into the offal collection tank, and a pump unit (9) operatively connectable to the discharge, wherein the apparatus further comprises a preservative reservoir (7) mounted on top of the collection tank (3). A collection and preservation system is provided, wherein the addition of preservation agent can be strictly controlled, can easily and quickly be installed and connected when it is to be used. After use, the system is easily removed and cleaned.

COMPOSITION FOR THE CONSERVATION/FIXATION OF BIOLOGICAL MATERIAL
20190208766 · 2019-07-11 ·

This invention relates to a liquid-based composition consisting of a mixture of methylethylketone peroxide between 30 and 40%, Methylethylketone between 0 and 5%, hydrogen peroxide between 0 and 5%, diisobutrate of 1-Isopropyl-2,2-Dimethyltrimethylene between 40 and 50% and Diacetone alcohol between 5 and 10%, isobutyl alcohol and glycerol and its use for the fixation and/or conservation of organic material such as isolated organs and tissues, cells of animal or vegetable origin. The invention also relates to a method for the embalming of corpses comprising the injection of such composition into the blood and/or lymphatic vascular system of an animal or vegetable organism.

COMPOSITION FOR THE CONSERVATION/FIXATION OF BIOLOGICAL MATERIAL
20190208766 · 2019-07-11 ·

This invention relates to a liquid-based composition consisting of a mixture of methylethylketone peroxide between 30 and 40%, Methylethylketone between 0 and 5%, hydrogen peroxide between 0 and 5%, diisobutrate of 1-Isopropyl-2,2-Dimethyltrimethylene between 40 and 50% and Diacetone alcohol between 5 and 10%, isobutyl alcohol and glycerol and its use for the fixation and/or conservation of organic material such as isolated organs and tissues, cells of animal or vegetable origin. The invention also relates to a method for the embalming of corpses comprising the injection of such composition into the blood and/or lymphatic vascular system of an animal or vegetable organism.

POST MORTEM RECONSTITUTION OF CIRCULATION
20190213918 · 2019-07-11 ·

A system for reconstituting circulation in a cadaver includes at least a pump, a fluid driven by the pump, and operative fluid connections between the pump and the cadaver. The system may be used to occlude one or more arterioles within the cadaver. The system may include a first circuit that creates a first fluid path with vessels of the cadaver, with first circuit having a first fluid conduit, a heater unit, a first pump, and a resistance device. The system may also include a second circuit that creates a second fluid path with vessels of the cadaver that are different from the vessels of the first circuit, with the second circuit having a second fluid conduit and a second pump. Alternately, the system may include a first circuit that creates a first fluid path with vessels of the cadaver and a second flow path that creates a second fluid path with the reservoir, where the first circuit includes a first conduit, a second connector, a pump, a reservoir, and a connector.

POST MORTEM RECONSTITUTION OF CIRCULATION
20190213918 · 2019-07-11 ·

A system for reconstituting circulation in a cadaver includes at least a pump, a fluid driven by the pump, and operative fluid connections between the pump and the cadaver. The system may be used to occlude one or more arterioles within the cadaver. The system may include a first circuit that creates a first fluid path with vessels of the cadaver, with first circuit having a first fluid conduit, a heater unit, a first pump, and a resistance device. The system may also include a second circuit that creates a second fluid path with vessels of the cadaver that are different from the vessels of the first circuit, with the second circuit having a second fluid conduit and a second pump. Alternately, the system may include a first circuit that creates a first fluid path with vessels of the cadaver and a second flow path that creates a second fluid path with the reservoir, where the first circuit includes a first conduit, a second connector, a pump, a reservoir, and a connector.

CLOSURE APPARATUS
20190208767 · 2019-07-11 ·

An apparatus for keeping a deceased person's mouth closed is disclosed herein. The apparatus ensures that the deceased person's mouth does not open during a period of muscle relaxation that immediately follow death, and ensures that the deceased mouth is not open during rigor mortis, which makes it more difficult to close the deceased open mouth later. The apparatus is comprised of various modular and swappable elements to ensure universal fit, as well as anti-slippage elements that ensure that the apparatus does not slip off a person's body when in use.

CLOSURE APPARATUS
20190208767 · 2019-07-11 ·

An apparatus for keeping a deceased person's mouth closed is disclosed herein. The apparatus ensures that the deceased person's mouth does not open during a period of muscle relaxation that immediately follow death, and ensures that the deceased mouth is not open during rigor mortis, which makes it more difficult to close the deceased open mouth later. The apparatus is comprised of various modular and swappable elements to ensure universal fit, as well as anti-slippage elements that ensure that the apparatus does not slip off a person's body when in use.

ANTIMICROBIAL COMPOSITIONS COMPRISING MINOCYCLINE AND DEGRADATION PRODUCTS OF OXIDIZED CELLULOSE

Provided is an antimicrobial composition comprised of at least one degradation product of oxidized cellulose (OC), such as oxidized regenerate cellulose (ORC), and minocycline, methods of preparation thereof and uses thereof.