A bioreactor for preferably three-dimensional cell culturing comprises a scaffold chamber, a first tube, a second tube and a first valve with a scaffold adapter, a tube adapter and a medium adapter. The first valve has a housing with a longitudinal female portion ending in an opening and a longitudinal actuator being arranged through the opening of the female portion of the housing such that the actuator is arranged partially inside the housing and partially outside the housing, wherein the actuator of the first valve is axially moveable relative to the housing of the first valve between a first position in which the first valve is in the operation position and a second position in which the first valve is in the medium change position. By providing the actuators in the first valve which is applied by axial movements, operation of the bioreactor can be comparably simple and safe.

The invention refers to a composition for the fixation of histological preparations, comprising a solution of glyoxal, wherefrom acids, normally present in the commercially available glyoxal, have been removed. The composition of the invention provides an optimal fixative for the preservation of structure, antigenic components and nucleic acids in tissues. The acid-free glyoxal has limited toxicity, is not considered as a carcinogenic agent and represents a valid alternative to formalin for the fixation of tissues and cells.

The invention refers to a composition for the fixation of histological preparations, comprising a solution of glyoxal, wherefrom acids, normally present in the commercially available glyoxal, have been removed. The composition of the invention provides an optimal fixative for the preservation of structure, antigenic components and nucleic acids in tissues. The acid-free glyoxal has limited toxicity, is not considered as a carcinogenic agent and represents a valid alternative to formalin for the fixation of tissues and cells.

A method for detecting a texture of Takifugu obscurus, including: (S1) removing internal organs and skin of the Takifugu obscurus followed by washing and drying; and removing a head and cutting a flesh on two sides of the Takifugu obscurus along a spine; (S2) cutting a plurality of cylindrical samples with the same shape and size along both sides of the flesh followed by transfer to a pre-cooled petri dish; allowing a cross section of the samples to cling to the petri dish followed by fixing with a petri dish cover; and storing the petri dish in seal at 0-4° C.; (S3) detecting, by a texture analyzer, a texture of each cylindrical sample; and averaging detection results of the samples as a result of the texture of the Takifugu obscurus.

A method for detecting a texture of Takifugu obscurus, including: (S1) removing internal organs and skin of the Takifugu obscurus followed by washing and drying; and removing a head and cutting a flesh on two sides of the Takifugu obscurus along a spine; (S2) cutting a plurality of cylindrical samples with the same shape and size along both sides of the flesh followed by transfer to a pre-cooled petri dish; allowing a cross section of the samples to cling to the petri dish followed by fixing with a petri dish cover; and storing the petri dish in seal at 0-4° C.; (S3) detecting, by a texture analyzer, a texture of each cylindrical sample; and averaging detection results of the samples as a result of the texture of the Takifugu obscurus.

Described herein are methods for producing multiple disinfecting agents from oils and reactors for producing multiple disinfecting agents from oils.

A method for treating a plastic block comprising using heat to embed a UV resistant material into an outer face of the plastic block wherein, once embedded, the UV resistant material provides a coating on the outer face. A method for treating a plastic block comprising using compressive force to embed a UV resistant material into an outer face of the plastic block wherein, once embedded, the UV resistant material provides a coating on the outer face.

A process for making and using a tissue preservation gel. The gel is comprised of water, reticulated acrylic acid, water soluble short-chain paraben, isopropyl alcohol and either triethanolamine or propylene glycol. To use the gel, a tissue to be preserved is first bathed in hypertonic sodium chloride, then soaked in a wash in multiple increasing concentrations of isopropyl alcohol and then preserved indefinitely in the tissue preservation gel.

The present inventive concept provides non-toxic compositions including ethanol, a polymer, and a polar aprotic solvent and methods of using the same in the field of preservation of plant, human and non-human animal tissue and anatomic pathology disciplines (e.g., surgical pathology, histopathology, cytopathology, forensic pathology). In particular, the compositions provide a safer alternative to aldehyde-based compositions.

A method for treating tissue to form a dry tissue component that is readily rehydrated and does not require rinsing prior to implantation in the human body. The method comprises pretreatment and fixation steps that include penetrating agent molecules having a flexible backbone and at least one polar group; the steps further include cations and anions to enhance integration of penetration agent molecules into and bonding to tissue component structural molecules to provide resistance to cracking of the dry tissue component during bending.