A lightweight reinforced mesh, such as a surgical mesh, suitable for use in various applications, including breast reconstruction, cosmetic breast surgery, mastopexy, breast augmentation, breast reduction, soft tissue reconstruction, hernia repair, tissue plication reinforcement, tissue support and repair, tendon support and repair, tissue engineering, and procedures or other applications requiring additional soft tissue strength or thickness. In addition, disclosed is a use of such a mesh for tissue engineering, regardless of the surgical application. In particular, the present disclosure relates to a surgical mesh capable of providing enhanced support while maintaining flexibility, low density, and absorbable characteristics. Further the present disclosure, focuses on reducing the material burden of a scaffold while increasing void space to facilitate tissue ingrowth.

A treatment instrument including a heat transmitter that includes a treating surface and an installation surface, a substrate attached to the installation surface, and a heat generator formed on a surface of the substrate. The substrate surface and heat generator together form an uneven surface. First and second adhesion layers formed of a material having thermal conductivity and electrical insulation are provided between the installation surface and the substrate. The first adhesion layer is in close contact with the installation surface, and the second adhesion layer is in close contact with the heat generator and the substrate surface. The second adhesion layer is inserted into a recess in the uneven surface formed by the heat generator on substrate surface so as to increase the contact area between the second adhesion layer and the uneven surface.

The present disclosure, for example, can include a laminated type patch A, comprising a release layer 1, a drug layer 2, a drug support layer 3 having elasticity, an adhesive layer 4, and an adhesive support layer 5 laminated in this order, wherein the outer edges of the release layer, the adhesive layer, and the adhesive support layer are all outside the outer edges of both the drug layer and the drug support layer; wherein the portion surrounded by the outer edges of the drug layer and the drug support layer, and the inner sides of the release layer and the adhesive layer has a space; and wherein the cross-sectional area of the space is 0.3 mm2 or more, at least when cut along the longitudinal centerline and the transverse centerline on the plane surfaces of the drug layer and the drug support layer.

The invention relates to a method for producing a carrier layer with a hydrophilic polymeric nanocoating wherein a polymeric carrier layer is produced with filaments of polymer material(s). Further the hydrophilic polymer nanocoating is applied by means of a low pressure plasma polymerization process using organic precursor monomers onto the polymeric carrier layer and/or composite membrane. Additionally, the invention relates to a carrier layer with a polymeric hydrophilic nanocoating.

The present invention relates to multi-layered composite structures and to methods for the preparation thereof. The present multi-layered composite structures are light weight and capable of high load bearing making the present multi-layered composite structures especially suitable to be used as load bearing structures in, for example, automotive. Specifically, the present invention relates to methods comprising the steps of a) providing a mould for said multi-layered composite structure; b) layering said mould with two or more layers forming the outer surface of said multi-layered composite; c) filling said layered mould with a mixture comprised of non-expanded heat-expandable microspheres and closing said mould; and d) subjecting said closed mould to a temperature of 80° C. to 140° C. during 1 to 230 minutes thereby providing a relative pressure in said closed mould of 0.1 to 20 bar through expansion of said heat-expandable microspheres thereby forming a multi-layered composite structure in said mould with a foam enforced inner core and a multi-layered outer surface; and e) separating the multi-layered composite structure from said mould.

The apparatuses and methods described herein relates generally to the field of active agent (drug) release from surgical grafts useful for soft tissue reconstruction, regeneration, or repair. More particularly, described herein are surgical grafts for soft tissue repair that include active agent that is released over time while advantageously matching the biomechanical properties of tissue during healing and recovery.

Arrangements described herein relate to systems, apparatuses, and methods for a disposable kit containing medical items configured for a medical device including a head cradle to support a head of a subject, the disposable kit includes a container that encloses a head cradle pad configured to be affixed to the head cradle, at least one fiducial marker configured to be disposed on a location at the head of the subject, and at least one enclosure configured to cover a portion of the medical device.

This invention relates to novel scar management products and methods of reducing dermal scars resulting from various types of dermal injuries while simultaneously reducing pruritis. Particularly, this invention relates to scar management products, each of which incorporate an antipruritic agent, that reduce and/or prevent dermal scarring and pruritis.

Product-shipping assembly containing a plurality of water-soluble articles are provided.

Disclosed aspects relate to a structure which includes shape memory materials having transition triggers to transition the shape memory materials between initial states and transitioned states. A first physical shape of the structure exists when the first shape memory material has the first initial state and the second shape memory material has the second initial state. A second physical shape of the structure exists when the first shape memory material has the first transitioned state and the second shape memory material has the second initial state. A third physical shape of the structure exists when the first shape memory material has the first transitioned state and the second shape memory material has the second transitioned state. The physical shapes of the structure are reversible in nature. In embodiments, the shape memory materials are bonded to a flexible substrate or are clad together.