A caster protection structure protects a caster provided at a base of a housing and used for transporting the housing in a movable manner, and includes a frame member that is provided at the base of the housing, serves as a part of a frame constituting the base of the housing, and extends in a predetermined direction. A longitudinal end position of the frame member is disposed in an outer region located beyond an outer lateral edge position of the caster.

A shock absorbing component for a luggage wheel is disclosed. In one practice, the component comprises a resilient circular member comprising an outer circumference; a center hole comprising an incompressible sleeve inserted into the center hole and configured to receive a wheel axle; and a plurality of openings radially disposed between the outer circumference and the center hole, the plurality of openings configured to resiliently deform to absorb shock when the circular member is subjected to force along its longitudinal axis. A wheel assembly for an article of luggage and an article of luggage comprising the shock absorbing component are also separately disclosed.

A system for sensing the angular position of a caster wheel includes a sensor mounted on a bearing which supports a shaft aligned with the rotational axis of the caster. A target on the shaft is detected by the sensor which generates signals indicative of the presence or absence of the target. The position of the target is coordinated with the position of the caster wheel such that the signals are indicative of the angular position of the caster wheel. The target may be a groove extending partially around the shaft and a remaining ungrooved portion of the shaft.

The invention provides a caster including two wheels, a central frame member, and a mount member. The two wheels are mounted on the mount member. The caster has a hybrid bearing arrangement comprising both a rolling bearing and two slide bearings. The rolling bearing is located between the central frame member and the mount member and is configured to enable the caster to roll along a straight line with each of the two wheels rotating in a common direction about a first axis. Each of the two slide bearings is located between the mount member and a tread portion of a respective one of the two wheels. The slide bearings are configured to enable the two wheels to simultaneously rotate in opposite directions when the caster swivels about a second axis orthogonal to the first axis. In some embodiments, the caster is a hubless caster.

A rolling device having a bearing housing accommodating a wheel axle carrying a wheel element, axle support members rotatably accommodated in the bearing housing and supporting the wheel axle, end portions of the wheel axle being connected to the axle support members in an eccentric position displaced from the rotational axis/4 line of the axle support members, a drive wheel connected to one of the axle support members for the axle support member to rotate following the rotation of the drive wheel, a first drive motor having a spindle engaged with the drive wheel to rotate the drive wheel and thereby the axle support member relative to the bearing housing, to displace the wheel element by eccentric movement between an extended position where at least a portion of the wheel element projects outside the bearing housing and a retracted position where the wheel element is located inside the bearing housing.

The present invention relates to stabilization of RNA, in particular mRNA, and an increase in mRNA translation. The present invention particularly relates to a modification of RNA, in particular in vitro-transcribed RNA, resulting in increased transcript stability and/or translation efficiency. According to the invention, it was demonstrated that certain sequences in the 3′-untranslated region (UTR) of an RNA molecule improve stability and translation efficiency.

The present invention relates to stabilization of RNA, in particular mRNA, and an increase in mRNA translation. The present invention particularly relates to a modification of RNA, in particular in vitro-transcribed RNA, resulting in increased transcript stability and/or translation efficiency. According to the invention, it was demonstrated that certain sequences in the 3′-untranslated region (UTR) of an RNA molecule improve stability and translation efficiency.

An apparatus and method for storing medical products such as pharmaceutical and medical products in climate controlled storage devices includes climate control systems in communication with inventory access and tracking systems.

An apparatus and method for storing medical products such as pharmaceutical and medical products in climate controlled storage devices includes climate control systems in communication with inventory access and tracking systems.