B65B3/00

Non-addictive analgesic sustained-release drug delivery system and preparation method thereof

A non-addictive analgesic sustained-release drug delivery system, comprising: (1) a narcotic analgesic drug having a concentration of 1 mg/ml-160 mg/ml, the drug being selected from a group consisting of: a local analgesic drug, and the combination of the local analgesic drug and a nonsteroidal analgesic drug and/or an opioid analgesic drug; (2) a drug menstruum in a proportion of 1%-75% (v/v), the menstruum being selected from a group consisting of benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release formulation having a proportion of 25%-99% (v/v), the sustained-release formulation being selected from a group consisting of natural vegetable oil, synthetic lipid, artificially improved half-natural lipid and derivative thereof. Also disclosed are a preparation process and use of the sustained-release drug delivery system.

PROCESSES FOR THE PRODUCTION OF SALINE SOLUTION BAGS
20220185509 · 2022-06-16 ·

Processes for the production of bags containing saline solution. The processes include sealing bags with crystalline components and then sterilizing the sealed bags with crystalline components. The bags may be sterilized in an autoclave and then transported to a consumption site which produces water-for-injection (WFI) suitable for use in an IV bag. The WFI is added to the sterilized bags, dissolving the solid salt (USP-grade sodium chloride), to produce a bag with a 0.9 w/v % normal saline solution.

PHARMACEUTICAL ORDER PROCESSING SYSTEMS AND METHODS
20220185510 · 2022-06-16 ·

A pharmaceutical container processor for processing pharmaceutical containers includes a set of container operation stations along which a set of container operations occur. The set of container operation stations includes a storage station where pharmaceutical containers are stored; a first identification station where pharmaceutical containers are each identified; a labeling station where a label is applied to pharmaceutical containers; a second identification station where pharmaceutical containers are each identified after the label is applied; and an outlet station where pharmaceutical containers are moved to after said pharmaceutical containers are identified at the second identification station. First and second container transporters move each pharmaceutical container through the set of container operation stations. Each pharmaceutical container is transferred from the first container transporter to the second container transporter along the set of container operation stations.

Transfer set with floating needle for drug reconstitution

An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial includes a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial. The adapter includes a needle assembly having a first tip and a second tip, with the needle assembly disposed within the housing and at least partially supported by a needle holder. The needle assembly is movable relative to the housing from an initial position in which the first and second tip are isolated from the cartridge and vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, establishing fluid communication therebetween. The needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing.

Test apparatus for checking container products
11353406 · 2022-06-07 · ·

A test apparatus checks containers (13) of plastic and produced using the blow-moulding, filling and sealing methods. The containers are filled with fluid that can contain particulate contamination deposited on the container wall when the container (13) is still and floating freely in the fluid when the container (13) is moving and/or changing position owing to the movement. The contamination can be detected by a sensor (37). By a vibration device (23), the container (13) can be oscillated at a prespecifiable excitation frequency such that the particulate contamination (47) in the fluid can be detected.

Liquid Aloe and Polyacrylamide Cold Pack
20220168138 · 2022-06-02 ·

Improvements in the cold pack with a sustained temperature of between 17-40 degrees Fahrenheit for over 2 hours and as long as 9 hours. The aloe and polyacrylamide cold pack can be configured so it does not continually condense or drip water for over 2 hours when using the ingredients of Ammonium C12-C15, Pareth Sulfate Ammonium C12-C15, Pareth Sulfate, Sodium Chloride, Poloxamer 124 DMDM Hydantoin Pent sodium Pentatate, Sodium Bisulfite. The main ingredients in regulating the ice pack temperature, longevity and hardness is the aloe, H2O and polyacrylamide ratio.

Systems, Methods, and Apparatuses for Producing and Packaging Fluids

A liquid concentrate generation system may comprise a manifold having an inlet receptacle including a first piercing member, an outlet receptacle including a second piercing member, and a flow channel connecting the inlet receptacle and outlet receptacle. The system may further comprise a cartridge having an inlet port and an outlet port sealed by a respective first and second cover. The inlet and outlet port may be respectively configured to displace within the inlet receptacle and outlet receptacle from an unspiked position to a spiked position. First and second piercing members may be in communication with the flow channel and spaced apart respectively from the first and second cover in the unspiked position. The first and second piercing members may be isolated from the flow channel and may respectively puncture the first and second cover in the spiked position.

Automated electromechanical capper for removing or securing a cap on a container
11741775 · 2023-08-29 · ·

The present invention is an automated electromechanical gripper for handling a container. In one embodiment, the gripper is used in an automated liquid dispenser. The gripper can grab a single container, remove the container from a nested stack of containers, and move the container in three directions (horizontally, laterally, and vertically).

Automated electromechanical capper for removing or securing a cap on a container
11741775 · 2023-08-29 · ·

The present invention is an automated electromechanical gripper for handling a container. In one embodiment, the gripper is used in an automated liquid dispenser. The gripper can grab a single container, remove the container from a nested stack of containers, and move the container in three directions (horizontally, laterally, and vertically).

Prefilled syringe and method of preparing a prefilled syringe

A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.