A product includes a use indicator carried inside a container so that, upon removal of a closure from the container or upon removal of flowable product from within the container, a coloration of the product changes irreversibly to indicate to a user that the package has been used.

A product includes a use indicator carried inside a container so that, upon removal of a closure from the container or upon removal of flowable product from within the container, a coloration of the product changes irreversibly to indicate to a user that the package has been used.

A strainable bag with a hook-and-hook closure can include walls formed of a material having multiple layers of polymer or paper or mixtures thereof, and which can include at least one gusset. The hook-and-hook closure allows for liquids or gases to be vented from the bag, as well as for liquids to be removed from the bag interior. The bag can be formed into a full open mouth configuration for ease of filling and ease of dispensing product. The hook-and-hook closure also allows for an imprecise alignment of the closure track to substantially close the bag around the gusset area. Methods of using and manufacturing a strainable bag with a hook-and-hook closure for preparing various food products are also presented.

This invention relates to novel acetylcysteine compositions in solution, comprising acetylcysteine and which are substantially free of metal chelating agents, such as EDTA. Further, this invention relates to methods of making and using the acetylcysteine compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time maintaining the stability of the pharmaceutical formulation. The compositions and methods of this invention are useful in the treatment of acetaminophen overdose, acute liver failure, various cancers, methacrylonitrile poisoning, reperfusion injury during cardio bypass surgery, and radiocontrast-induced nephropathy, and can also be used as a mucolytic agent.

Apparatus for filling devices that are penetrable for filling the devices with a substance, and resealable for sealing the resulting hole. A device support supports at least one such device in a substantially fixed position relative to the support during filling and/or resealing. A manifold drivingly mounted over the device support can include (1) a cartridge including a filling needle for penetrating a resealable stopper and introducing a substance therethrough into the device, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold can include a thermal source for heating a penetrated region of the stopper and, sealing the hole.

System, hardware, and methods for agitating a package pre-form containing a charge of product elements thus to provide for product settling in the package pre-form before forming the final transverse seal. The product is caused to settle in the package pre-form by apply a plurality of rapid jerk-type acceleration forces to the packaging material, thus to cause rapid longitudinal and/or lateral acceleration in the packaging material.

System, hardware, and methods for agitating a package pre-form containing a charge of product elements thus to provide for product settling in the package pre-form before forming the final transverse seal. The product is caused to settle in the package pre-form by apply a plurality of rapid jerk-type acceleration forces to the packaging material, thus to cause rapid longitudinal and/or lateral acceleration in the packaging material.

A Cartridge (2; 2; 2) for a stereolithography machine (1), including a container (3) provided with an access opening (4), a reservoir (5) for containing a base material (6), liquid or pasty, suited to be solidified through exposure to a predefined radiation (7), said reservoir (5) being permanently associated with said container (3), feeding means (8) suited to feed said base material (6) from said reservoir (5) towards said container (3), characterized in that the bottom (9) of said container (3) is at least partially transparent to said predefined radiation (7) and is situated opposite said access opening (4).

A Cartridge (2; 2; 2) for a stereolithography machine (1), including a container (3) provided with an access opening (4), a reservoir (5) for containing a base material (6), liquid or pasty, suited to be solidified through exposure to a predefined radiation (7), said reservoir (5) being permanently associated with said container (3), feeding means (8) suited to feed said base material (6) from said reservoir (5) towards said container (3), characterized in that the bottom (9) of said container (3) is at least partially transparent to said predefined radiation (7) and is situated opposite said access opening (4).

The disclosure describes a system for applying custom branded tape to packages that are shipped from a multi-seller materials handling facility. In some implementations, a materials handling facility may store, process and ship items for multiple sellers. As items are packed for shipping, a tape dispensing device may dispense custom branded tape associated with the seller of the item(s) being packed such that the sellers brand, logo or other information is presented on the exterior of the container.