A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

Disclosed is a device useful for preserving tissue samples after extraction from human or animal patients. The device includes a circular blade for taking a tissue sample, the blade being coupled to a sealing cap which mates to one end of a container. A retrieval port is also disclosed for extracting fluids from the container. Methods are also disclosed by which tissue samples may be taken and prepared for storage, processing, culture, or other analysis.

An oral care implement that includes a head having a face with a tuft hole therein. A plurality of bristles are disposed within the tuft hole and arranged in a bristle tuft that extends from the face of the head. The bristle tuft includes a first subset of the bristles and a second subset of the bristles. Each of the bristles has a longitudinal axis and a transverse cross-sectional profile having a major axis and a minor axis, the major axes of the bristles being longer than the minor axes of the bristles. The major axes of the bristles of the first subset may be non-parallel to the major axes of the bristles of the second subset.

A conduit seal assembly includes an outer conduit having a first end with a first opening and a second end, opposite the first end, with a second opening. A first seal is positioned in the first opening for resisting a first temperature, and a second seal is positioned in the second opening for resisting a second temperature less than the first temperature. The first and second seals define a cavity and provide an air-tight seal of the cavity, and the assembly includes a monitoring assembly configured to sense a characteristic in the cavity.

A closure for a container has a base and a lid. The base is attachable to the container. The lid is pivotally connected to the base and moveable between open and closed positions. The lid or the base has operating tabs on its periphery. Each operating tab has an actuation portion and an engagement portion. The engagement portion is moveable between engagement and disengagement positions. When the lid is in the closed positioned, the engagement portion engages the other of the lid and the base in the engagement position and disengages from the other of the lid and the base in the disengagement position. The actuation portion of the operating tab is resiliently deflectable radially outward relative to the one of the lid and the base to move the engagement portion to the disengagement position whereupon release of the actuation portion, the engagement portion returns to the engagement position.

Disclosed is an airtight container having a deformable cover unit or a deformable container unit, which ensures easy maintenance of the cover unit and allows the cover unit to be easily used with a large-capacity fixed container unit, or which includes an expandable accommodating space or an expandable inlet to accommodate various sizes of storage items therein in an airtight manner. The airtight container includes a deformable cover unit for useable with a fixed container unit. Alternatively, the airtight container includes first and second frames pivotably connected to each other so as to be selectively coupled to or come into contact with each other in order to seal a contact or coupling portion therebetween, and a deformable container unit disposed over the frames and configured to provide an accommodating space for a storage item therein. The first and second frames are disposed along the inlet rim of the container unit.

Disclosed is an airtight container having a deformable cover unit or a deformable container unit, which ensures easy maintenance of the cover unit and allows the cover unit to be easily used with a large-capacity fixed container unit, or which includes an expandable accommodating space or an expandable inlet to accommodate various sizes of storage items therein in an airtight manner. The airtight container includes a deformable cover unit for useable with a fixed container unit. Alternatively, the airtight container includes first and second frames pivotably connected to each other so as to be selectively coupled to or come into contact with each other in order to seal a contact or coupling portion therebetween, and a deformable container unit disposed over the frames and configured to provide an accommodating space for a storage item therein. The first and second frames are disposed along the inlet rim of the container unit.

A vial assembly may include a vial having a body to hold a liquid material, and a neck extending from the body. The neck may include a multi-use surface configured to permit access to the liquid material. The vial assembly may include a cap to be received by the neck and to cover the multi-use surface. The cap may include a base having a first major surface, and a second major surface opposite of the first major surface, arms extending from the second major surface, and a rupturable reservoir of disinfectant material carried by the base between the first major surface and the second major surface. One or more of the first major surface and the second major surface may be flexible so as to rupture the rupturable reservoir when the cap is received by the neck.

A closure assembly for a cell culture apparatus includes a port and a snap cap. The port has an annular sidewall defining an opening in communication with a cell culture chamber of a cell culture apparatus. The sidewall has (i) external threads for cooperating with internal threads of a twist cap and (ii) an annularly protruding snap cap engagement feature. The snap cap has a top and an annular sidewall extending from the top. The sidewall of the snap cap has an inwardly annularly projecting element configured to engage with the annularly protruding snap cap engagement feature of the port such that, when fully engaged, the snap cap is not readily removed from the port by unaided human force.

A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer(s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.