To modify the headspace in a container to remove vacuum pressure, a container has a seal or cap which may provide a temporary opening into the container which is sealable under compression to provide a controlled raising of the internal pressure as the heated contents of the container cools. A sealing chamber (84) may enable the introduction of a fluid into the headspace (23b) to force the fluid level (40) lower. Other methods and apparatus are described.

Synthetic resin bottle (1) including tube-shaped body section (3) comprises eight decompression absorbing panels (8) disposed at equal intervals in body section (3) and pillar sections (9) respectively disposed between said decompression absorbing panels (8) and formed by arcuate wall surfaces (9a). Arcuate wall surfaces (9a) of pillar sections (9) in a cross section of body section (3) configure parts of one imaginary perfect circle (10). A total of circumferential lengths of arcuate wall surfaces (9a) of pillar sections (9) is 20 to 50% of a total circumferential length of perfect circle (10). Consequently, it is possible to realize the synthetic resin bottle having decompression absorbing performance in order to absorb a decrease in internal pressure, the exterior of the body section of the synthetic resin bottle being seen as a cylindrical shape whose shape is almost the same as that of a perfect circle.

A deposition mask package according to the present embodiment includes a receiving portion, a lid portion that faces the receiving portion, a deposition mask that is arranged between the receiving portion and the lid portion and has an effective region in which a plurality of through-holes is formed. The receiving portion has a first opposing surface facing the lid portion and a concave portion provided on the first opposing surface. The concave portion is covered by a first flexible film. The effective region of the deposition mask is arranged on the concave portion with the first flexible film interposed therebetween.

Base includes an outer support wall, a support surface extending inwardly from the outer support wall and defining a reference plane, an inner support wall extending upwardly from the support surface, a first radiused portion extending radially inward from the inner support wall and concave relative to the reference plane, a second radiused portion extending radially inward from the first radiused portion and convex relative to the reference plane, an intermediate surface extending radially inward from the second radiused portion, the intermediate surface including a linear portion and an intermediate radiused portion, a third radiused portion extending radially inward from the intermediate surface and convex relative to the reference plane, and a central portion disposed proximate the third radiused portion.

A transport pouch includes a flap portion and a body portion separated from each other by a folding portion. The transport pouch also includes a front panel and a rear panel, an adhesive closure, at least one removable cover, and a form closure. When the flap portion of the transport pouch is folded onto the body portion of the transport pouch, the flap area of the adhesive closure is adhered to the body area of the adhesive closure, and the form closure is closed, the folding portion of the transport pouch acts as a barrier that prevents billowing of the body portion of the transport pouch, caused by a relative pressure increase in the transport space due to a pressure drop in the surroundings of the transport pouch, from tearing open the form closure and thus from tearing open the adhesive closure.

A pull tab crown for a bottle or other container provides an opener secured to the top of the crown. The crown has an annular skirt with an annular edge. Score lines extend from the opener assembly to the skirt. One of the score lines is curvilinear and terminates at the annular edge. A second score line has a segment that extends from the opener assembly to an endpoint substantially spaced from the bottom annular edge of the skirt.

A heat-resistant and biaxially stretched blow-molded plastic container includes a base movable to accommodate vacuum forces generated within the container and thereby decrease the volume of the container. Embodiments of a container include a push-up portion, and first and second parting lines that are separated from one another by a gap and that extend on opposite sides of the push-up portion. Embodiments of such a container exhibit one or more of the following: (a) a distance between each parting line and the center of the base is not more than 20 mm; (b) a distance between the two parting lines is not more than 40 mm; and/or (c) a distance between the two parting lines is less than 50% of the transverse dimension of the base measured between the two outermost points of the parting lines. Methods for blow molding heat-resistant plastic containers are also disclosed.

An extrusion blow-molded plastic container, for example, a plastic bottle, is described which has a container body having a longitudinal axis, a longitudinal end sealed by a container bottom, another longitudinal end adjoining a container neck provided with a pour opening, and a container shoulder. The container body has at least one deformable section which is made flat and which extends over a large part of an axial length of the container body and in the peripheral direction. The deformable section which has been made flat has two longitudinal sides which run essentially in the axial direction and which border regions of the container body which have a greater stiffness than the deformable section.

A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I:

##STR00001##

or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I:

##STR00001##

or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.