The invention relates to a method of making a functionalized nanoparticle in an aqueous solution, wherein a chemical functionalization of a metal nanoparticle in the aqueous solution is provided and the aqueous solution comprises water and ingredients. The ingredients comprise at least the metal nanoparticle, a thiol of the form R—SH, where R represents a substituent, and a silver compound. The invention further relates to a plurality of functionalized nanoparticles according to the method, wherein each of the plurality of functionalized nanoparticles comprises a metal core, a silver coating and a sulfide bond substituent. The invention also relates to a lateral flow test method and device.

The present invention relates to a gold nanoparticle-containing medicine, and a treatment of a proliferative disease using the medicine. The present invention also relates to a gold nanoparticle-containing medicine that is bound to an alpha radioactive nucleus, and a treatment of a proliferative disease using the medicine.

A manufacturing method of a quantum dot ensemble of the present disclosure is a manufacturing method of a quantum dot ensemble including a plurality of core-shell quantum dots 10A that each includes a core 10B including a compound semiconductor, and a shell 10C including a compound semiconductor and covering the core, and a ligand 10D coordinated to the shell, and the manufacturing method includes mixing a core material, a shell material, and the ligand in a solvent and thereafter performing heating to thereby form the core-shell quantum dots, coordinate the ligand to the shell, and cleave the ligand.

A manufacturing method of a quantum dot ensemble of the present disclosure is a manufacturing method of a quantum dot ensemble including a plurality of core-shell quantum dots 10A that each includes a core 10B including a compound semiconductor, and a shell 10C including a compound semiconductor and covering the core, and a ligand 10D coordinated to the shell, and the manufacturing method includes mixing a core material, a shell material, and the ligand in a solvent and thereafter performing heating to thereby form the core-shell quantum dots, coordinate the ligand to the shell, and cleave the ligand.

The invention concerns a biocompatible oily ferrofluid comprising iron-oxide based magnetic nanoparticles and an oil phase comprising at least one fatty acid ester, characterized in that said magnetic nanoparticles are surface functionalized by molecules of one or more phospholipids, and in particular a biocompatible oily ferrofluid comprising iron-oxide based magnetic nanoparticles and an oil phase comprising at least one fatty acid ester, said iron-oxide based magnetic nanoparticles forming a colloidal dispersion in said oil phase from a temperature belonging to the range from 20 to 80° C., characterized in that said magnetic nanoparticles are surface functionalized by molecules of one or more phospholipids which do not completely cover the surface of the iron-oxide based magnetic nanoparticles, which in particular ensure a coverage rate of the surface of the iron-oxide based magnetic nanoparticles such that the fatty acid ester(s) present in the oil phase have access to the surface of the iron-oxide based magnetic nanoparticles. The invention also concerns the process for preparing such a biocompatible oily ferrofluid and its use as a contrast agent for magnetic resonance imaging or in the context of a cancer treatment by hyperthermia. Finally, the invention concerns a nanoemulsion comprising such a biocompatible oily ferrofluid.

The present disclosure provides nanoparticles comprising methyl palmitate and at least one serumglobular protein and uses thereof.

Synthesizing Janus material including forming a lamellar phase having water layers and organic layers, incorporating nanosheets and a functional agent into the lamellar phase, and attaching the functional agent to the nanosheets in the lamellar phase to form Janus nanosheets.

Methods for forming polyolefin nanocomposite precursor compositions are provided. In embodiments, such a method comprises mixing a polyolefin, unmodified graphite, and a peroxide crosslinker via solid-state shear pulverization under conditions to form a polyolefin nanocomposite precursor composition comprising the polyolefin; exfoliated, unmodified graphite dispersed throughout the polyolefin; and unreacted peroxide crosslinker dispersed throughout the polyolefin, wherein the polyolefin is polyethylene, a copolymer of polyethylene, or combinations thereof. Methods of forming crosslinked polyolefin nanocomposites, the polyolefin nanocomposite precursor compositions, and crosslinked polyolefin nanocomposites are also provided.

Metastable alloys have recently emerged as high-performance catalysts, extending the toolbox of binary alloy materials that can be utilized to mediate electrocatalytic reactions. In particular, nanostructured metastable ordered intermetallic compounds are particularly challenging to synthesize. Here the present invention is directed to a method for synthesizing sub-15 nm metastable ordered intermetallic Pd31Bi12 nanoparticles at room temperature, in a single step, by pulsed electrochemical deposition onto high surface area carbon supports. The resulting Pd31Bi12 nanoparticles displays a 7× enhancement of the mass activity relative to Pt/C and a 4× enhancement relative to Pd/C for the oxygen reduction reaction (ORR). The high performance of Pd31Bi12 nanoparticles is demonstrated to arise from reduced oxygen binding caused by alloying of Pd with Bi. The isolation of Pd-sites from each other facilitate methanol tolerant ORR behavior.

A disaggregation method for NDs (nanodiamonds) comprising: sonicating NDs dispersed in water; and sedimenting non-disaggregated NDs by centrifugation. Optionally, the method includes sonicating the disaggregated NDs with CAN [(NH.sub.4).sub.2Ce(NO.sub.3).sub.6] to produce CAN modified NDs and washing to remove excess CAN. Populations of disaggregated NDs are also disclosed. In some embodiments the populations are provided as an aqueous suspension.