Embodiments of the present invention pertain to antimicrobial glass compositions, glasses, and articles. The articles include a glass, which may include a glass phase and a cuprite phase. In other embodiments, the glasses include a plurality of Cu.sup.1+ ions, a degradable phase including B.sub.2O.sub.3, P.sub.2O.sub.5 and K.sub.2O, and a durable phase including SiO.sub.2. Other embodiments include glasses having a plurality of Cu.sup.1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The article may also include a polymer. The glasses and articles disclosed herein exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing condition and under Modified JIS Z 2801 for Bacteria testing conditions.

A ceramic composition includes an antimicrobial glass composition that includes components harmless to the human body and maintains an antimicrobial function semi-permanently. Specifically, the ceramic composition includes a novel antimicrobial glass composition that includes a glass former SiO.sub.2 as a main component, and ZnO and SnO as antimicrobial components.

A ceramic composition includes an antimicrobial glass composition that includes components harmless to the human body and maintains an antimicrobial function semi-permanently. Specifically, the ceramic composition includes a novel antimicrobial glass composition that includes a glass former SiO.sub.2 as a main component, and ZnO and SnO as antimicrobial components.

A method of manufacture of a dental prosthesis is described, comprising using a rotary milling or drilling tool (16) to mill or drill a block (12) of a sintered ceramic material. The use of a tool (16) to mill or drill material from a block (12) of a sintered ceramic material such as lithium silicate or lithium disilicate allows manufacture of a glass ceramic dental prosthesis in a relatively efficient manner.

The present invention relates to a glass ceramic material comprising a core-rim structure, wherein the core-rim structure comprises an amorphous SiO.sub.2 matrix, ZrO.sub.2 crystals, and hardness-enhancing additive, the ZrO.sub.2 crystals are present in cores that are at least partly surrounded by a rim comprising hardness-enhancing additive.

There is disclosed an antibacterial glass composite and a manufacturing method thereof. The antibacterial glass composite may include 15 to 40% by weight (wt) of SiO.sub.2: 20 to 40% wt of B.sub.2O.sub.3: 10 to 30% wt of at least one of Na.sub.2O, K.sub.2O and Li.sub.2O; to 15% wt of at least one of MgO and TiO.sub.2; 5 to 40% wt of at least one of ZnO and CaO; to 10% wt of CuO; and 0.1 to 3% wt of Ag.sub.2O, thereby having an anti-biofilm effect.

There is disclosed an antibacterial glass composite and a manufacturing method thereof. The antibacterial glass composite may include 15 to 40% by weight (wt) of SiO.sub.2: 20 to 40% wt of B.sub.2O.sub.3: 10 to 30% wt of at least one of Na.sub.2O, K.sub.2O and Li.sub.2O; to 15% wt of at least one of MgO and TiO.sub.2; 5 to 40% wt of at least one of ZnO and CaO; to 10% wt of CuO; and 0.1 to 3% wt of Ag.sub.2O, thereby having an anti-biofilm effect.

The present disclosure provides glass compositions that include from 45 mol% to about 95 mol% of B203; from about 3 mol% to about 60 m ol% of one or more glass components selected from the group consisting of: K20, Na20, CaO, and MgO; and from about 2 mol% to about 45 mol% of CaF.sub.2, SnF.sub.2, NaF, KF, Na.sub.2PO.sub.3 F, or a combination thereof, where the glass includes less than 30 mol% of CaF.sub.2, SnF.sub.2, or a combination thereof. The glass includes: substantially no CuO; less than 0.1 mol% of Li.sub.20, less than 0.1 mol% of Rb.sub.2O, less than 0.1 mol% of BaO; less than 0.1 mol% of P.sub.20.sub.5; less than 0.1 mol% SiO.sub.2; and less than 30 mol% of MgO. The glass composition may be used to desensitize dentin. The present disclosure also provides dentin-desensitizing compositions, as well as methods and uses of the disclosed glass compositions.

The present disclosure provides glass compositions that include from about 20 mol % to 45 mol % of B.sub.2O.sub.3; and from about 10 mol % to about 80 mol % of one or more glass components selected from the group consisting of CaO and MgO. The glass compositions also include less than 0.1 mol % CdO. The glass compositions may include one or more of Na.sub.2O, K.sub.2O, and a phosphate source, where the B2O3 and the phosphate source total about 60 mol % or less. The glass compositions may include a source of fluoride. The glass composition may be used to desensitize dentin. The present disclosure also provides dentin-desensitizing compositions, as well as methods and uses of the disclosed glass compositions.

A glass (excluding glass used for optical elements selected from the group consisting of lenses and prisms and glass used for optical fibers) has an oxide-basis glass composition based on a mass basis of a SiO.sub.2 content of 0 to 25%, a B.sub.2O.sub.3 content of 0 to 35%, a P.sub.2O.sub.5 content of 0 to 30%, a total content of SiO.sub.2, B.sub.2O.sub.3, and P.sub.2O.sub.5 (SiO.sub.2+B.sub.2O.sub.3+P.sub.2O.sub.5) of 10 to 45%, an Al.sub.2O.sub.3 content of 0 to 15%, a Li.sub.2O content of 0 to 2%, a Na.sub.2O content of 0 to 10%, a K.sub.2O content of 0 to 10%, a Rb.sub.2O content of 0 to 5%, a Cs.sub.2O content of 0 to 5%, a total content of Li.sub.2O, Na.sub.2O, K.sub.2O, Rb.sub.2O, and Cs.sub.2O (Li.sub.2O+Na.sub.2O+K.sub.2O+Rb.sub.2O+Cs.sub.2O) of 0 to 15%, and has a wetting angle to water of 60° or more.