C07C45/00

Chemical intermediates by catalytic fast pyrolysis process

In this invention, a portion of the products from a pyrolysis reactor are reacted in a process to form one or more chemical intermediates.

Pt-DPEphos-iodine complex and Pt-DPEphos-bromine complex

Pt-DPEphos-iodine complex and Pt-DPEphos-bromine complex, and use thereof for catalysis of a hydroformylation reaction.

Pt-xanthene-iodine complex and Pt-xanthene-bromine complex

Pt-xanthene-iodine complex and Pt-xanthene-bromine complex, and use thereof for catalysis of a hydroformylation reaction.

Pt-biphenyl-iodine complex and Pt-biphenyl-bromine complex

Pt-biphenyl-iodine complex and Pt-biphenyl-bromine complex, and the use thereof for catalysis of a hydroformylation reaction.

Pt-xanthene-bromine complex

Pt-xanthene-bromine complex, and use thereof for catalysis of a hydroformylation reaction.

FORMATION OF CHROMANES BASED ON INTERMOLECULAR REACTION OF ALKYNES WITH DIMETHYLFURAN IN THE PRESENCE OF GOLD(I) COMPLEXES
20170349563 · 2017-12-07 ·

The present invention relates to a method of preparing chromanes from 2,5-dimethylfuran and substituted alkynes comprising an long chain unsaturated alkyl group as substituent in the alpha position of a substituted phenol followed by oxidation, reduction and acid ring closure. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of β-tocopherol.

FORMATION OF CHROMANES BASED ON INTERMOLECULAR REACTION OF ALKYNES WITH DIMETHYLFURAN IN THE PRESENCE OF GOLD(I) COMPLEXES
20170349563 · 2017-12-07 ·

The present invention relates to a method of preparing chromanes from 2,5-dimethylfuran and substituted alkynes comprising an long chain unsaturated alkyl group as substituent in the alpha position of a substituted phenol followed by oxidation, reduction and acid ring closure. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of β-tocopherol.

1,3-Di-oxo-indene derivative, pharmaceutically acceptable salt or optical isomer thereof, preparation method thereof, and pharmaceutical composition containing same as an antiviral, active ingredient

Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

1,3-Di-oxo-indene derivative, pharmaceutically acceptable salt or optical isomer thereof, preparation method thereof, and pharmaceutical composition containing same as an antiviral, active ingredient

Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

NOVEL METHOD FOR CATALYTIC DEHYDRATION OF GLYCEROL TO ACROLEIN

A novel method for catalytic dehydration of glycerol to acrolein is provided. A fixed bed reactor is used, which is placed in a microwave unit. The feedstock is introduced into the fixed bed reactor after being preheated and gasified. Continuous glycerol dehydration occurs in the presence of a microwave-absorbing catalyst in the fixed bed reactor to form acrolein. The microwave-absorbing catalyst is composed of an active component loaded on a core-shell structure which consists of microwave absorbent coated by an oxide. The uniformity of microwave heating can reduce the formation of hot spot during the reaction and hence improve the catalyst stability. The process and operation is simple, and the unit can steadily run for a long time.