The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

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The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

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A method of processing an aqueous hemicellulosic stream containing lignin, comprising: (a) contacting an aqueous hemicellulosic stream containing lignin with a C.sub.3-8 alkyl alcohol at elevated temperature and acidic pH; (b) separating the reaction mixture obtained from step (a) into an aqueous phase containing hemicellulose-derived monosaccharide and an organic phase containing C.sub.3-8 alkyl alcohol; (c) concentrating the organic phase obtained from step (b) to remove at least some C.sub.3-8 alkyl alcohol; (d) treating the residue from step (c) with water or an aqueous medium having an alkaline pH; and (e) recovering C.sub.3-8 alkyl alcohol from the product of step (d).

A method of processing an aqueous hemicellulosic stream containing lignin, comprising: (a) contacting an aqueous hemicellulosic stream containing lignin with a C.sub.3-8 alkyl alcohol at elevated temperature and acidic pH; (b) separating the reaction mixture obtained from step (a) into an aqueous phase containing hemicellulose-derived monosaccharide and an organic phase containing C.sub.3-8 alkyl alcohol; (c) concentrating the organic phase obtained from step (b) to remove at least some C.sub.3-8 alkyl alcohol; (d) treating the residue from step (c) with water or an aqueous medium having an alkaline pH; and (e) recovering C.sub.3-8 alkyl alcohol from the product of step (d).

A process for recycling a first article to be recycled including a composite material based on a fibrous reinforcer and a thermoplastic, preferably (meth)acrylic, polymer matrix, wherein the recycling process includes the following steps: introduction of the first article into a system suitable for the recycling of thermoplastic polymer, introduction, into the system suitable for the recycling of thermoplastic polymer, of a second article to be recycled including a thermoplastic polymer resin, and not including any fibrous reinforcer, heating of the articles to be recycled at a given temperature, in the system suitable for recycling thermoplastic polymer, so as to depolymerize the thermoplastic, preferably (meth)acrylic, polymers, and to form base monomers of the thermoplastic polymers, and recovery of the constituent base monomers of the thermoplastic polymers.

A process for recycling a first article to be recycled including a composite material based on a fibrous reinforcer and a thermoplastic, preferably (meth)acrylic, polymer matrix, wherein the recycling process includes the following steps: introduction of the first article into a system suitable for the recycling of thermoplastic polymer, introduction, into the system suitable for the recycling of thermoplastic polymer, of a second article to be recycled including a thermoplastic polymer resin, and not including any fibrous reinforcer, heating of the articles to be recycled at a given temperature, in the system suitable for recycling thermoplastic polymer, so as to depolymerize the thermoplastic, preferably (meth)acrylic, polymers, and to form base monomers of the thermoplastic polymers, and recovery of the constituent base monomers of the thermoplastic polymers.

Subject-matter of the invention is a process for the preparation of a key intermediate in the synthesis of indacaterol. Subject-matter of the invention are also new synthesis intermediates. Formula (I):

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Subject-matter of the invention is a process for the preparation of a key intermediate in the synthesis of indacaterol. Subject-matter of the invention are also new synthesis intermediates. Formula (I):

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Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.