A means of isolating specific stereoisomers and enantiomers from a complex mixture containing a possibility of 32 different stereoconfigurations, thus concentrating the stereoisomer or enantiomer to a high degree of purity.

Provided is a fluorinated ether compound capable of imparting excellent antifouling properties such as oil-based ink repellency, fingerprint stain removability, to a hard coating layer; a composition for forming a hard coating layer, and an article having an antifouling hard coating layer formed from the composition. The fluorinated ether compound has either a poly(oxyperfluoroalkylene) chain having a repeated unit that includes a C.sub.1-2 oxyperfluoroalkylene group and a C.sub.3-6 oxyperfluoroalkylene group, bonded to each other, or a poly(oxyperfluoroalkylene) chain having a repeated unit that contains a C.sub.4 oxyperfluoroalkylene group and a different oxyperfluoroalkylene group, bonded to each other, a linking group bonded to a first terminal of the poly(oxyperfluoroalkylene) chain, and at least one (meth)acryloyl group bonded to the linking group.

An acrylic or methacrylic compound having N-alkoxyalkyl group; and a method for producing the compound. An acrylic or methacrylic compound having N-alkoxyalkyl group, of Formula [1]: ##STR00001##
[where R.sup.1 is a hydrogen atom or methyl group; R.sup.2 is a C.sub.2-20 alkylene group etc.; R.sup.3 is an r-valent C.sub.2-20 aliphatic group etc.; R.sup.4 is a C.sub.1-20 alkyl group etc.; Z is >NCOO or OCON< (where - is a bond, > and < each have two bonds, and any one of > and < is bonded to CH.sub.2OR.sup.4); and r is a natural number of 2 or more and 9 or less].

The invention relates to compounds of the formula ##STR00001## and to a process for making same and to the use of the products in the solid phase peptide synthesis. The compounds of formula I are versatile peptide intermediates for the solid phase peptide synthesis (SPPS) of peptide drugs which comprise a Glu-fatty alkyl side chain building block attached to a Lys-part of the peptide chain.

The present invention relates to using a two-step (thermolysis) or one-pot process to prepare aliphatic diisocyanates from aliphatic diamines and diaryl carbonates. Polyisocyanates can also be prepared from polyamines and diaryl carbonates. The present synthetic processes do not apply phosgene or highly toxic reagents and chloro-solvents during the entire procedure.

The invention is directed to a method of treating bipolar disorder in a subject, comprising administering a therapeutically effective amount of a carbamate compound, or pharmaceutically acceptable salt or amide thereof.

The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing multiple sclerosis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of neurodegenerative diseases and other neuro-inflammatory diseases.