A polycarbodiimide composition is a reaction product of polyisocyanate having a primary isocyanate group and alcohols, wherein in an infrared absorption spectrum, the intensity ratio (IR.sub.CI/IR.sub.UI+U) of absorbance IR.sub.CI at or near 2120 cm.sup.1 due to stretching vibration of the carbodiimide group relative to absorbance IR.sub.UI+U at or near 1720 cm.sup.1 due to stretching vibration of the uretonimine group and urethane group is 1.5 or more and 4.5 or less.

A polycarbodiimide composition is a reaction product of polyisocyanate having a primary isocyanate group and alcohols, wherein in an infrared absorption spectrum, the intensity ratio (IR.sub.CI/IR.sub.UI+U) of absorbance IR.sub.CI at or near 2120 cm.sup.1 due to stretching vibration of the carbodiimide group relative to absorbance IR.sub.UI+U at or near 1720 cm.sup.1 due to stretching vibration of the uretonimine group and urethane group is 1.5 or more and 4.5 or less.

The present invention relates to processes for producing polymeric carbodiimides by addition of cesium salts and to polymeric carbodiimides produced by this process and to the use thereof as a hydrolysis inhibitor, especially in polyurethane (PU)-based systems, preferably thermoplastic TPU, PU adhesives, PU casting resins, PU elastomers or PU foams.

A polycarbodiimide composition is a reaction product of polyisocyanate having a primary isocyanate group and alcohols, wherein in an infrared absorption spectrum, the intensity ratio (IR.sub.CI/IR.sub.UI+U) of absorbance IR.sub.CI at or near 2120 cm.sup.1 due to stretching vibration of the carbodiimide group relative to absorbance IR.sub.UI+U at or near 1720 cm.sup.1 due to stretching vibration of the uretonimine group and urethane group is 1.5 or more and 4.5 or less.

The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (I), wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5 and n have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyperproliferative disorders, in particular for cancer, respectively tumour disorders. The present invention furthermore relates to the use of SMYD2 inhibitors for benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, neurodegenerative disorders, inflammatory disorders, atherosclerotic disorders and the control of male fertility.

##STR00001##

The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (I), wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5 and n have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyperproliferative disorders, in particular for cancer, respectively tumour disorders. The present invention furthermore relates to the use of SMYD2 inhibitors for benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, neurodegenerative disorders, inflammatory disorders, atherosclerotic disorders and the control of male fertility.

##STR00001##

This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (Formula One and Formula Two).

##STR00001##

This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (Formula One and Formula Two).

##STR00001##

An inhibitor of a prostate specific membrane antigen and a pharmaceutical use thereof. Specifically, the present solution belongs to the field of radiopharmaceuticals and relates to a compound represented by formula (IV) or a pharmaceutically acceptable salt thereof.

##STR00001##

An improved method of coupling amino acids into peptides or peptidomimetics is disclosed in which the activation and coupling are carried out in the same vessel, in the presence of a carbodiimide in an amount greater than 1 equivalent as compared to the amino acid, in the presence of an activator additive, and at a temperature greater than 30 C.