A method for producing a nitrogen-containing pentafluorosulfanylbenzene compound of formula (2a) or (2b): ##STR00001## (wherein R.sup.1 a hydrogen atom or a hydrocarbon group; Z is an aryl group linked to a carbonyl group; Y is a group of formula (Y1), (Y2), (Y3), or (Y4); R.sub.2 is a hydrogen atom or a hydrocarbon group) ##STR00002## the method comprising reacting a halogeno-pentafluorosulfanylbenzene compound of formula (1) with a nitrogenous nucleophile: ##STR00003## (wherein X is a halogen atom; n is an integer of 1 to 5; R.sup.1 is as defined above).

A method for producing a nitrogen-containing pentafluorosulfanylbenzene compound of formula (2a) or (2b): ##STR00001## (wherein R.sup.1 a hydrogen atom or a hydrocarbon group; Z is an aryl group linked to a carbonyl group; Y is a group of formula (Y1), (Y2), (Y3), or (Y4); R.sub.2 is a hydrogen atom or a hydrocarbon group) ##STR00002## the method comprising reacting a halogeno-pentafluorosulfanylbenzene compound of formula (1) with a nitrogenous nucleophile: ##STR00003## (wherein X is a halogen atom; n is an integer of 1 to 5; R.sup.1 is as defined above).

Provided is a compound of Formula (I):

##STR00001## wherein the variable groups are defined herein.

A solution is a compound represented by formula (1), a liquid crystal composition containing the compound and a liquid crystal display device including the composition. ##STR00001## In formula (1), R.sup.a and R.sup.b are independently alkyl having 1 to 30 carbons or the like; and X and Y are independently fluoroalkyl having 1 to 5 carbons, fluoroalkoxy having 1 to 5 carbons or pentafluorosulfanil, and one of X and Y may be fluorine.

A solution is a compound represented by formula (1), a liquid crystal composition containing the compound and a liquid crystal display device including the composition. ##STR00001## In formula (1), R.sup.a and R.sup.b are independently alkyl having 1 to 30 carbons or the like; and X and Y are independently fluoroalkyl having 1 to 5 carbons, fluoroalkoxy having 1 to 5 carbons or pentafluorosulfanil, and one of X and Y may be fluorine.

An aryloyl(oxy or amino)pentafluorosulfanylbenzene compound having pharmacological action. The aryloyl(oxy or amino)pentafluorosulfanylbenzene compound is represented by general formula (A-I), a pharmaceutically acceptable salt thereof, and a prodrug thereof, ##STR00001##
wherein all of parameters represent the same meanings as defined in the specification.

An aryloyl(oxy or amino)pentafluorosulfanylbenzene compound having pharmacological action. The aryloyl(oxy or amino)pentafluorosulfanylbenzene compound is represented by general formula (A-I), a pharmaceutically acceptable salt thereof, and a prodrug thereof, ##STR00001##
wherein all of parameters represent the same meanings as defined in the specification.

Industrial methods for producing arylsulfur pentafluorides are disclosed. Methods include reacting arylsulfur halotetrafluoride with hydrogen fluoride in the absence or presence of one or more additives selected from a group of fluoride salts, non-fluoride salts, and unsaturated organic compounds to form arylsulfur pentafluorides.

Industrial methods for producing arylsulfur pentafluorides are disclosed. Methods include reacting arylsulfur halotetrafluoride with hydrogen fluoride in the absence or presence of one or more additives selected from a group of fluoride salts, non-fluoride salts, and unsaturated organic compounds to form arylsulfur pentafluorides.

The invention relates to compounds of formula (I), wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to LFA-1 integrin antagonists to target cells expressing LFA-1. ##STR00001##