Patent classifications
C07D247/00
SULFONYL-SUBSTITUTED BENZOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD AND MEDICAL USE THEREOF
The present invention relates to a sulfonyl-substituted benzoheterocyclic derivative, a preparation method and medical use thereof. Particularly, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, and a preparation method and application thereof. The definition of each group in the formula can be found in the specification and the claims.
##STR00001##
METHOD FOR PRODUCING TRIARYLORGANOBORATES
The invention relates to a process for preparing triaryl organoborates proceeding from organoboronic esters in the presence of an n-valent cation 1/n K.sup.n+, comprising the anhydrous workup of the reaction mixture and the use of the triaryl organoborates obtained as co-initiator in photopolymer formulations, holographic media and holograms.
HIV PROTEASE INHIBITORS
The invention provides a compound of Formula I:
##STR00001##
or a pharmaceutically acceptable salt thereof as described herin. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.
HIV PROTEASE INHIBITORS
The invention provides a compound of Formula I:
##STR00001##
or a pharmaceutically acceptable salt thereof as described herin. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.
Class of organic phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting
The invention provides a lighting device including a light source configured to generate light source light and a light converter configured to convert at least part of the light source light into visible converter light. The light converter includes a matrix containing a luminescent material based on derivatives of benzimidazoxanthenoisoquinolinone. The lighting device may include a further luminescent material.
Class of organic phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting
The invention provides a lighting device including a light source configured to generate light source light and a light converter configured to convert at least part of the light source light into visible converter light. The light converter includes a matrix containing a luminescent material based on derivatives of benzimidazoxanthenoisoquinolinone. The lighting device may include a further luminescent material.
Method for producing triarylorganoborates
The invention relates to a process for preparing triaryl organo borates proceeding from organoboronic esters in the presence of an n-valent cation 1/n K.sup.n+, comprising the anhydrous workup of the reaction mixture and the use of the triaryl organoborates obtained as co-initiator in photopolymer formulations, holographic media and holograms.
Method for producing triarylorganoborates
The invention relates to a process for preparing triaryl organo borates proceeding from organoboronic esters in the presence of an n-valent cation 1/n K.sup.n+, comprising the anhydrous workup of the reaction mixture and the use of the triaryl organoborates obtained as co-initiator in photopolymer formulations, holographic media and holograms.
Debriding Dressing For Use With Negative Pressure And Fluid Instillation
Systems, methods, and apparatuses for debriding a tissue site are described. The system includes a manifold and a cover adapted to form a sealed space over the tissue site for providing negative pressure. The system also includes a debridement tool positioned between the manifold and the tissue site. The debridement tool having a tissue-facing surface and a plurality of holes separated from each other by walls. The walls have transverse surfaces extending between the tissue-facing surface and an opposite surface that form cutting edges. The holes have a perforation shape factor that allows the holes to collapse from a relaxed position to a contracted position in response to the application and removal of negative pressure from the sealed space. The cutting edges debride the tissue site in response to movement between the relaxed position and the contracted position.
CD73 COMPOUNDS
Provided herein is A compound of Formula I:
##STR00001## or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.