C07D403/00

SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES
20200369889 · 2020-11-26 ·

Described herein are embodiments of squarylium compounds for use as filters in light-emitting and/or display devices. One problem of known quarylium dyes is that strong nucleophiles can attack the electron-deficient cyclobutene ring which can lead to a loss of the dye's colour. Another potential drawback with squaraine dyes can be their tendency to form aggregates, which can lead to a substantial broadening of their absorption bands. Use of the present compounds in filters address these problems. The squarylium compounds of the present invention have the following formulas:

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CIRCULARLY POLARIZING PLATE

Provided is a circularly polarizing plate that is excellent in antireflection characteristic, and that can be produced at low cost. The circularly polarizing plate of the present invention includes in the stated order: a polarizer; a retardation layer (20a) configured to function as a /4 plate; and a colored layer, wherein an angle formed by an absorption axis of the polarizer and a slow axis of the retardation layer (20a) is from 35 to 55, wherein the colored layer has an absorption peak in a wavelength band in a range of from 580 nm to 610 nm, and wherein the colored layer contains a compound X represented by the general formula (I) or the general formula (II).

OPTICAL LAYERED BODY

Provided is an optical laminate having the following feature: when the optical laminate is used in an image display apparatus, the optical laminate can express a sufficient brightness, can express a satisfactory hue, and can achieve a cost reduction while suppressing a reflectance. The optical laminate of the present invention includes: a wavelength conversion layer; and an absorption layer arranged on one side of the wavelength conversion layer, wherein the absorption layer has an absorption peak in a wavelength band in a range of from 580 nm to 610 nm, and wherein the absorption layer contains a compound x represented by the general formula (I) or the general formula (II).

POLYCYCLIC COMPOUND ACTING AS IDO INHIBITOR AND/OR IDO-HDAC DUAL INHIBITOR
20200276180 · 2020-09-03 ·

Compounds as IDO inhibitors and/or dual inhibitors of IDO-HDAC are described. Specifically, the compounds represented by the following formula (I) are described, wherein each group is defined as described in the specification. The compounds have IDO inhibitory activity or IDO-HDAC dual inhibitory activity and can be used for preventing or treating diseases associated with IDO and/or IDO-HDAC activity or expression levels. At the same time, the compounds of the present invention can be combined with an anti-tumor antibody such as PD-1 and PD-L1, and such a combination can greatly increase the anti-tumor response rate of the antibody and broaden the types of tumors to be treated.

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Purine inhibitors of human phosphatidylinositol 3-kinase delta

The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer. ##STR00001##

Agents for alleviating side effects

The present invention provides an agent for alleviating side effects caused by use of an anti-tumor agent, which contains 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H-pyrimidi nedione (1) represented by formula (1): ##STR00001##
or a pharmaceutically acceptable salt thereof. The 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione or a pharmaceutically acceptable salt thereof exhibit an inflammatory-suppressing action in the digestive tract and advantageously alleviate diarrhea and loss of body weight concomitant with administration of a chemical for treating cancer without suppressing the anti-tumor effect. Thus, the compounds of the present invention are of great value as agents for alleviating side effects caused by use of an anti-tumor agent, which enable not only the chemotherapy to be continuedly carried out, but also the body exhaustion to be effectively prevented.

ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE

An organic electroluminescence device includes an anode, an emitting layer and a cathode. The emitting layer includes a first compound and a second compound. The first compound is a delayed fluorescent compound. The second compound is a fluorescent compound. A solution of the second compound in toluene has an emission peak wavelength in a range from 430 nm to 480 nm. A molar absorbance coefficient of the second compound at an absorption peak closest to a long-wavelength side is in a range from 29,000 L/(mol.Math.cm) to 1,000,000 L/(mol.Math.cm). The second compound has a Stokes shift in a range from 1 nm to 20 nm.

Hole transport compositions and related devices and methods (I)

A composition comprising: at least one compound comprising a hole transporting core, wherein the core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group different from the first, and wherein the compound is covalently bonded to at least one intractability group, wherein the intractability group is covalently bonded to the hole transporting core, the first arylamine group, the second arylamine group, or a combination thereof, and wherein the compound has a molecular weight of about 5,000 g/mole or less. Blended mixtures of arylamine compounds, including fluorene core compounds, can provide good film formation and stability when coated onto hole injection layers. Solution processing of OLEDs is a particularly important application.

Hole transport compositions and related devices and methods (I)

A composition comprising: at least one compound comprising a hole transporting core, wherein the core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group different from the first, and wherein the compound is covalently bonded to at least one intractability group, wherein the intractability group is covalently bonded to the hole transporting core, the first arylamine group, the second arylamine group, or a combination thereof, and wherein the compound has a molecular weight of about 5,000 g/mole or less. Blended mixtures of arylamine compounds, including fluorene core compounds, can provide good film formation and stability when coated onto hole injection layers. Solution processing of OLEDs is a particularly important application.

Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof
10093633 · 2018-10-09 · ·

The present invention provides novel functionalized mixtures 4- and 5-vinyl substituted regioisomers of 1,2,3-triazoles via 1,3-dipolar cycloaddition. Functionalized alkyne moieties with a terminal alcoholic functionality are reacted with functionalized organic moieties with a terminal leaving group and an azide to provide an alcoholic functionalized mixture of 4- and 5-substituted regioisomers of 1,2,3-triazole moieties. The mixture may be converted to a wide variety of useful functionalized mixtures of 4- and 5-vinyl substituted regioisomers of 1,2,3-triazole moieties, which in turn can be converted to a wide variety of useful polymers The novel alcoholic functionalized mixtures of 4- and 5-substituted regioisomers can be separated by chromatography to provide the purified 4- and 5-alcoholic functionalized substituted 1,2,3-triazole moieties. The novel compounds of the invention can be employed in a wide variety of compositions (Formulae (I), (II)); wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4, are defined herein. ##STR00001##