C07D405/00

1-aryl-3-alkylpyrazole insecticides

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, ##STR00001##
wherein Q is ##STR00002##
and Z, R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.2d, J.sup.1, J.sup.2 and M are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

1-aryl-3-alkylpyrazole insecticides

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, ##STR00001##
wherein Q is ##STR00002##
and Z, R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.2d, J.sup.1, J.sup.2 and M are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

Compound useful to treat mycoses

This invention relates to compounds, as defined in the specification and as represented by the compound of formula (I): ##STR00001##
that are useful in the treatment of mycoses, compositions containing them and their use in therapy.

Benzofuran analogue as NS4B inhibitor

Provided is a benzofuran analog having a structure represented by formula (I) and used as an NS4B inhibitor, or a pharmaceutically acceptable salt of the benzofuran analog. The benzofuran analog has anti-hepatitis C virus activity.

Compound useful to treat mycoses

This invention relates to a compound, as defined in the specification and as represented by the compound of formula (I): ##STR00001##
useful in the treatment of mycoses, to compositions containing it and its use in therapy.

N-sulfonyl homoserine lactone derivatives, preparation method and use thereof

The invention relates to a homoserine lactone derivative of Formula I, preparation method and use thereof. The compound has an effect of regulatory of bacterial quorum sensing, and is useful for preventing and/or treating a disease caused by infection of a bacterium ##STR00001##

Glutaminase inhibitors and method of use

Compounds and compositions comprising compounds that inhibit glutaminase are described herein. Also described herein are methods of using the compounds that inhibit glutaminase in the treatment of cancer.

N-Sulfonyl Homoserine Lactone Derivatives, Preparation Method and Use Thereof

The invention relates to a homoserine lactone derivative of Formula I, preparation method and use thereof. The compound has an effect of regulatory of bacterial quorum sensing, and is useful for preventing and/or treating a disease caused by infection of a bacterium.

##STR00001##

Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides

Malonic ester derivatives of the formula (I) ##STR00001##
in which the symbols A.sup.1, A.sup.2, Y, R.sup.10, p, X, R.sup.2, G, Q, L.sup.2 and R.sup.1 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).

Tackifier compounds and methods of using the same

The present invention relates to tackifier compounds and methods of using the same. In various embodiments, the present invention provides a tackifier compound including independently substituted or unsubstituted fused rings A and B each independently chosen from (C.sub.5-C.sub.10)cycloalkyl and (C.sub.2-C.sub.10)heterocyclyl. Fused ring A is substituted with (R.sup.1).sub.1-8 and fused ring B is substituted with (OC(O)RC(O)R.sup.2).sub.1-8. At each occurrence R is independently chosen from (C.sub.2-C.sub.10)alkanylene, (C.sub.2-C.sub.10)alkenylene, (C.sub.2-C.sub.10)alkynylene, C.sub.5-C.sub.20(arylene), and (C.sub.1-C.sub.20)heteroarylene, wherein R is unsubstituted or substituted. At each occurrence R.sup.1 is independently selected from OH, OR.sup.3, and OC(O)RC(O)R.sup.2. At each occurrence R.sup.2 is independently chosen from OH, OR.sup.3, NH.sub.2, NHR.sup.3, and NR.sup.3.sub.2. At each occurrence R.sup.3 is independently chosen from (C.sub.1-C.sub.10)alkanyl, (C.sub.2-C.sub.10)alkenyl, (C.sub.2-C.sub.10)alkynyl, C.sub.5-C.sub.20(aryl), and (C.sub.1-C.sub.20)heteroaryl, wherein R.sup.3 is unsubstituted or substituted.