The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens.

Described herein are prodrugs of heterocyclic compounds, compositions, and methods for their use for the treatment of disease.

The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens.

Copolymers having thiophene based and vinylene based moieties. Methods of producing the copolymers, and methods of utilizing the copolymers as chromogenic sensors for selective detection of iodide anion are also provided.

Copolymers having thiophene based and vinylene based moieties. Methods of producing the copolymers, and methods of utilizing the copolymers as chromogenic sensors for selective detection of iodide anion are also provided.

The present invention provides compounds, compositions thereof, and methods of using the same.

A compound of Chemical Formula 4 or 5: ##STR00001## wherein: one of X1 and X2 is a direct bond, and the other is O, S, or CY1Y2, one of X3 and X4 is a direct bond, and the other is O, S, or CY3Y4, W1 to W4 are each independently N or CRa, and one or more of W1 to W4 are N, Y1 to Y4 are the same as or different from each other, and are each independently an alkyl group having 1 to 20 carbon atoms, and the other substituents are as defined in the specification; and an organic light emitting device comprising the same. The compound can lower the driving voltage, improve the light efficiency, and enhance service life characteristics of the device due to thermal stability of the compound.

A compound of Chemical Formula 4 or 5: ##STR00001## wherein: one of X1 and X2 is a direct bond, and the other is O, S, or CY1Y2, one of X3 and X4 is a direct bond, and the other is O, S, or CY3Y4, W1 to W4 are each independently N or CRa, and one or more of W1 to W4 are N, Y1 to Y4 are the same as or different from each other, and are each independently an alkyl group having 1 to 20 carbon atoms, and the other substituents are as defined in the specification; and an organic light emitting device comprising the same. The compound can lower the driving voltage, improve the light efficiency, and enhance service life characteristics of the device due to thermal stability of the compound.

Compositions and methods of selectively activating Akt3 are provided.

Copolymers having thiophene based and vinylene based moieties. Methods of producing the copolymers, and methods of utilizing the copolymers as chromogenic sensors for selective detection of iodide anion are also provided.