The present disclosure describes compounds of the formula: (I), (II), (III), (IV), (V). The compounds described herein may be cyclooxygenase (COX) (e.g., cyclooxygenase 2 (COX2)) inhibitors. The compounds may be radiolabeled. The compounds (e.g., radiolabeled compounds) may be useful (e.g., as positron emission tomography (PET) imaging agents) for diagnosing a disease. The compounds may also be useful for treating or preventing a disease. The present disclosure also describes pharmaceutical compositions and kits including the compounds; and methods of using the compounds.

##STR00001##

The present disclosure describes compounds of the formula: (I), (II), (III), (IV), (V). The compounds described herein may be cyclooxygenase (COX) (e.g., cyclooxygenase 2 (COX2)) inhibitors. The compounds may be radiolabeled. The compounds (e.g., radiolabeled compounds) may be useful (e.g., as positron emission tomography (PET) imaging agents) for diagnosing a disease. The compounds may also be useful for treating or preventing a disease. The present disclosure also describes pharmaceutical compositions and kits including the compounds; and methods of using the compounds.

##STR00001##

The present invention discloses a fused heterocyclic compound of formula (I),

##STR00001##

wherein, Q, R.sup.1, R.sup.2, n, m and Y are as defined in the detailed description. The present invention further discloses methods for their preparation and use of the compounds of formula (I) as a pest control agent.

The present invention discloses a fused heterocyclic compound of formula (I),

##STR00001##

wherein, Q, R.sup.1, R.sup.2, n, m and Y are as defined in the detailed description. The present invention further discloses methods for their preparation and use of the compounds of formula (I) as a pest control agent.

The invention provides new heterocyclic compounds having the general formula (I)

##STR00001##

wherein A, B, L, Y.sup.1 to Y.sup.4 and R.sup.1 to R.sup.6 are as described herein.

The invention provides new heterocyclic compounds having the general formula (I)

##STR00001##

wherein A, B, L, Y.sup.1 to Y.sup.4 and R.sup.1 to R.sup.6 are as described herein.

The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such as pain, ADHD/ADD, alcohol use disorder, anxiety disorder, and dementias.

The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such as pain, ADHD/ADD, alcohol use disorder, anxiety disorder, and dementias.

The invention belongs to the technical field of agricultural chemicals, and in particular relates to a pyridazinol compound represented by the Formula I, a derivative, preparation method, herbicidal composition and use thereof. The compound, derivative and herbicidal composition thereof have very high herbicidal activity and selectivity, and are safe for crops,

##STR00001##

The present disclosure provides compounds having Formula I:

##STR00001##

and the pharmaceutically acceptable salts and solvates thereof, wherein X.sup.1, X.sup.2, X.sup.11, X.sup.12, R.sup.1, R.sup.3, R.sup.5, R.sup.5′, R.sup.6, and R.sup.7 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to inhibit a USP1 protein and/or to treat a disorder responsive to the inhibition of USP1 proteins and USP1 activity. Compounds of the present disclosure are especially useful for treating cancer.