Patent classifications
C07J9/00
OXYSTEROL COMPOUNDS AND USES THEREOF
Described herein are compounds and pharmaceutical compositions containing such compounds for the modulation of Hedgehog signaling.
OXYSTEROL COMPOUNDS AND USES THEREOF
Described herein are compounds and pharmaceutical compositions containing such compounds for the modulation of Hedgehog signaling.
Polymeric bile acid derivatives inhibit Hepatitis B and D virus and NTCP transport
The invention provides for treating HBV or HDV infection or inhibiting human sodium taurocholate co-transporting polypeptide (hNTCP) with a polymeric bile acid or salt thereof, and pharmaceutical compositions comprising a polymeric bile acid or salt thereof, and a second HBV or HDV medicament.
Polymeric bile acid derivatives inhibit Hepatitis B and D virus and NTCP transport
The invention provides for treating HBV or HDV infection or inhibiting human sodium taurocholate co-transporting polypeptide (hNTCP) with a polymeric bile acid or salt thereof, and pharmaceutical compositions comprising a polymeric bile acid or salt thereof, and a second HBV or HDV medicament.
VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES
Described are methods for preparing a deuterated aldehyde using with a photocatalyst and a hydrogen atom transfer agent in a H.sub.2O free solvent comprising D.sub.2O and an organic solvent under an inert gas. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions.
VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES
Described are methods for preparing a deuterated aldehyde using with a photocatalyst and a hydrogen atom transfer agent in a H.sub.2O free solvent comprising D.sub.2O and an organic solvent under an inert gas. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions.
Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds. ##STR00001##
Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds. ##STR00001##
Use of 20-hydroxyecdysone and the derivatives thereof in the treatment of myopathies
The invention relates to 20-hydroxyecdysone and the derivatives thereof, for use in the treatment of genetic myopathies.
Use of 20-hydroxyecdysone and the derivatives thereof in the treatment of myopathies
The invention relates to 20-hydroxyecdysone and the derivatives thereof, for use in the treatment of genetic myopathies.