C07K16/00

PURIFICATION OF MULTISPECIFIC ANTIBODIES
20230220114 · 2023-07-13 · ·

The present disclosure provides methods for purifying multispecific antibodies from a mispaired variant thereof by performing a multi-mode chromatography.

Process for the purification of recombinant antibody fragments

The present invention relates to a purification process of recombinant antibody fragments from inclusion bodies expressed in microbial cells. More particularly, the present invention relates to a process for purification of recombinant humanized (rHu) antibody fragment, Ranibizumab from inclusion bodies expressed in microbial cells.

Methods for purifying antibodies having reduced high molecular weight aggregates
11697670 · 2023-07-11 · ·

Provided herein, in some embodiments, are methods and compositions for purifying antibodies from cellular cultures using one or more thiol containing additives during a purification process, for example in a chromatographic purification process.

Methods for purifying antibodies having reduced high molecular weight aggregates
11697670 · 2023-07-11 · ·

Provided herein, in some embodiments, are methods and compositions for purifying antibodies from cellular cultures using one or more thiol containing additives during a purification process, for example in a chromatographic purification process.

Motile sperm domain containing protein 2 antibodies and methods of use thereof

The present disclosure relates to antibodies or antigen binding fragments thereof that specifically bind to Motile Sperm Domain Containing Protein 2 (MOSPD2) and methods of using the same.

Motile sperm domain containing protein 2 antibodies and methods of use thereof

The present disclosure relates to antibodies or antigen binding fragments thereof that specifically bind to Motile Sperm Domain Containing Protein 2 (MOSPD2) and methods of using the same.

NOVEL ANTIBODY FRAMEWORKS
20230212265 · 2023-07-06 ·

The present invention relates to novel antibody frameworks with advantageous properties.

NOVEL ANTIBODY FRAMEWORKS
20230212265 · 2023-07-06 ·

The present invention relates to novel antibody frameworks with advantageous properties.

BISPECIFIC FC MOLECULES
20230212297 · 2023-07-06 ·

Described herein is a bispecific molecule containing an Fc polypeptide chain and immunoglobulin variable regions. Also provided are pharmaceutical formulations comprising such molecules, nucleic acids encoding such molecules, host cells containing such nucleic acids, methods of making such molecules, and methods of using such molecules.

BISPECIFIC FC MOLECULES
20230212297 · 2023-07-06 ·

Described herein is a bispecific molecule containing an Fc polypeptide chain and immunoglobulin variable regions. Also provided are pharmaceutical formulations comprising such molecules, nucleic acids encoding such molecules, host cells containing such nucleic acids, methods of making such molecules, and methods of using such molecules.