A resin composition is provided. The resin composition comprises: (A) a compound having a structure of formula (I),

##STR00001## wherein R.sub.1 is an organic group; and (B) a vinyl-containing elastomer, wherein the weight ratio of the compound having the structure of formula (I) to the vinyl-containing elastomer is 20:1 to 1:1.

A multiblock, cationic-functionalized norbornene copolymer is formed by a process including performing a vinyl addition polymerization in the presence of a metal catalyst of a first norbornene monomer substituted with a first alkyl group and a second norbornene monomer substituted with a second alkyl group by adding a predetermined amount of the first norbornene monomer and a predetermined amount of the second norbornene monomer sequentially to the reaction to form blocks of an intermediate norbornene multiblock copolymer. The second alkyl group includes a substituent which undergoes a reaction with a precursor for a cationic group having a volume less than 0.25 cm.sup.3/mol. The process further includes reacting the precursor for the cationic group with the intermediate norbornene multiblock copolymer to form the multiblock, cationic-functionalized norborene copolymer.

A multiblock, cationic-functionalized norbornene copolymer is formed by a process including performing a vinyl addition polymerization in the presence of a metal catalyst of a first norbornene monomer substituted with a first alkyl group and a second norbornene monomer substituted with a second alkyl group by adding a predetermined amount of the first norbornene monomer and a predetermined amount of the second norbornene monomer sequentially to the reaction to form blocks of an intermediate norbornene multiblock copolymer. The second alkyl group includes a substituent which undergoes a reaction with a precursor for a cationic group having a volume less than 0.25 cm.sup.3/mol. The process further includes reacting the precursor for the cationic group with the intermediate norbornene multiblock copolymer to form the multiblock, cationic-functionalized norborene copolymer.

An alternating copolymer including a structural unit (a0-1) represented by general formula (a0-1) and a structural unit (a0-2) represented by general formula (a0-2) in which Rp.sup.01 represents a hydrogen atom or the like; Vp.sup.01 represents a single bond or a divalent linking group; Rp.sup.02 and Rp.sup.03 each independently represents a hydrocarbon group which may have a substituent, or Rp.sup.02 and Rp.sup.03 are mutually bonded to form a ring; Rp.sup.04 represents a hydrogen atom, a C1-C5 alkyl group or a C1-C5 halogenated alkyl group; Rp.sup.05 represents an alkyl group, an alkoxy group, a halogen atom, a halogenated alkyl group, a cyano group or a hydroxy group; Rp.sup.06 represents a linear or branched aliphatic hydrocarbon group; and m represents an integer of 0 to 4 ##STR00001##

An alternating copolymer including a structural unit (a0-1) represented by general formula (a0-1) and a structural unit (a0-2) represented by general formula (a0-2) in which Rp.sup.01 represents a hydrogen atom or the like; Vp.sup.01 represents a single bond or a divalent linking group; Rp.sup.02 and Rp.sup.03 each independently represents a hydrocarbon group which may have a substituent, or Rp.sup.02 and Rp.sup.03 are mutually bonded to form a ring; Rp.sup.04 represents a hydrogen atom, a C1-C5 alkyl group or a C1-C5 halogenated alkyl group; Rp.sup.05 represents an alkyl group, an alkoxy group, a halogen atom, a halogenated alkyl group, a cyano group or a hydroxy group; Rp.sup.06 represents a linear or branched aliphatic hydrocarbon group; and m represents an integer of 0 to 4 ##STR00001##

A statistical, cationic-functionalized norbornene copolymer is formed by a process including performing a vinyl addition polymerization in the presence of a metal catalyst of a first norbornene monomer substituted with a first alkyl group and at least a second norbornene monomer substituted with a second alkyl group, to form an intermediate norbornene copolymer. The second alkyl group includes a substituent which undergoes a substitution reaction with a precursor of a cationic group. The process further includes adding the precursor for the cationic group to the intermediate norbornene copolymer to form the cationic functionalized norbornene copolymer. The cationic group has a volume of 0.25 cm.sup.3/mol or greater (for example, a phosphonium group or an imidazolium group).

A statistical, cationic-functionalized norbornene copolymer is formed by a process including performing a vinyl addition polymerization in the presence of a metal catalyst of a first norbornene monomer substituted with a first alkyl group and at least a second norbornene monomer substituted with a second alkyl group, to form an intermediate norbornene copolymer. The second alkyl group includes a substituent which undergoes a substitution reaction with a precursor of a cationic group. The process further includes adding the precursor for the cationic group to the intermediate norbornene copolymer to form the cationic functionalized norbornene copolymer. The cationic group has a volume of 0.25 cm.sup.3/mol or greater (for example, a phosphonium group or an imidazolium group).

In an aspect, the invention provides therapeutic agents comprising brush polymers that address challenges associated with conventional administration of free therapeutic peptides. In an embodiment, for example, the invention provides brush polymers incorporating one or more therapeutic peptides as side chain moieties. Therapeutic agents of the invention comprising brush polymers include high-density brush polymers including cross-linked brush polymers and brush block copolymers. In an embodiment, brush polymers of the invention exhibit proteolysis-resistant characteristics and maintain their biological function during formulation and administration. The invention also includes methods of making and using therapeutic agents comprising brush polymers.

The present invention relates to a high performance cross-linked triblock cationic functionalized polymer for electrochemical applications, and methods of making and using the same. The invention also relates to a tunable hydrogenated polymer, that can be functionalized with a particular cation for a particular application, and the method of making the hydrogenated polymer and tuning the hydrogenated polymer for the application.

The present invention relates to a high performance cross-linked triblock cationic functionalized polymer for electrochemical applications, and methods of making and using the same. The invention also relates to a tunable hydrogenated polymer, that can be functionalized with a particular cation for a particular application, and the method of making the hydrogenated polymer and tuning the hydrogenated polymer for the application.